Phase 4
Completed N=463
Bupropion SR Plus Counseling for Smoking Cessation
Source: ClinicalTrials.gov NCT01621009 ↗Enrolled (actual)
463
Serious AEs
0.0%
Results posted
Jan 2016
Primary outcomePrimary: 7-day Point Prevalence Abstinence From Smoking at 6 Months — 21; 16; 15; 14 Number of abstinent participants — p=>0.05
Summary
The purpose of this study was to determine if bupropion plus counseling was more effective than bupropion alone or counseling alone in helping smokers quit smoking.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY 7-day Point Prevalence Abstinence From Smoking at 6 Months |
21; 16; 15; 14 | >0.05 |
Eligibility Criteria
Inclusion Criteria
- Smoke 10 or more cigarettes per day
- Expired carbon monoxide (CO) level greater than 9 parts per million (ppm)
- Motivated to quit smoking (score of 3 on 4-point self-report scale)
- Willing to fulfill study requirements
Exclusion Criteria
- Carbon monoxide breath test score below 9 ppm
- Serious psychopathology (bipolar disorder, psychosis)
- Center for Epidemiologic Studies Depression Scale CES-D)score over 16
- Contraindications for use of bupropion
- History of seizure disorder
- History of eating disorder
- Current heavy drinking
- Risk of pregnancy
- Current breastfeeding
Data sourced from ClinicalTrials.gov (NCT01621009). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.