Phase 1 N=58 Randomized Treatment

Persistence-Targeted Smoking Cessation

Tobacco Use Disorder

Bottom Line

View on ClinicalTrials.gov: NCT01654107 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Sep 2015

Primary outcome: Primary: 7-day Point Prevalence Abstinence — 4; 1 participants

Study Design & Population

Study type: Interventional
Phase: Phase 1
Interventions: Persistence Targeted Smoking Cessation (Behavioral); Clearing The Air (Behavioral); Nicotine lozenge (Drug)
Age: Adult · 18+ yrs
Sex: All
Sponsor: Rutgers, The State University of New Jersey
Primary completion: Sep 2014

Outcome Measures

Outcome	Result	p-value
PRIMARY 7-day Point Prevalence Abstinence	4; 1	—

Summary

The investigators propose to develop a theory-based smoking cessation intervention (called Persistence-targeted smoking cessation; PTSC). PTSC includes 8 weekly individual counseling sessions and use of nicotine lozenge for 12 weeks. The investigators will test the feasibility and preliminary efficacy of the intervention (i.e., cigarettes per day and prolonged abstinence).

Eligibility Criteria

Inclusion Criteria

Must be between 18 - 64 years old
Must smoke at least 10 cigarettes per day for past 6-months
Expired breath carbon monoxide (CO) > 7
Must have a working cellular phone

Exclusion Criteria

Must not be currently receiving tobacco dependence treatment counseling
Must not currently be taking varenicline, bupropion, or any nicotine preparations (gum, lozenge, patch, spray, inhaler)
Must have no contraindications to using nicotine lozenge

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01654107). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.