N/A
N=191
A Randomized Controlled Trial of Lung Ultrasound Compared to Chest X-ray for Diagnosing Pneumonia in the Emergency Department
Pneumonia
Bottom Line
View on ClinicalTrials.gov: NCT01654887 ↗Enrolled (actual)
191
Serious AEs
0.0%
Results posted
Mar 2017
Primary outcome: Primary: Percentage of Participants For Whom CXR Was Not Needed to Diagnose Pneumonia — 38.8; 0 percentage of participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Lung Ultrasound (Other); Chest X-Ray (Radiation)
- Age
- Pediatric, Adult
- Sex
- All
- Sponsor
- Icahn School of Medicine at Mount Sinai
- Primary completion
- Jul 2013
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percentage of Participants For Whom CXR Was Not Needed to Diagnose Pneumonia |
38.8; 0 | — |
| PRIMARY Percentage of Participants Whose Pneumonia Was Missed by LUS or CXR |
0.0; 0.0 | — |
| SECONDARY Comparison of Unscheduled Healthcare Visits |
8.7; 11.4 | — |
| SECONDARY Percentage of Participants With Antibiotic Use |
37.9; 27.3 | — |
| SECONDARY Percentage of Participants Who Had Hospital Admission. |
19.4; 17.0 | — |
| SECONDARY Comparison of the Length of Stay in the ED |
153; 180 | — |
Summary
The primary objective of this study is to determine if lung ultrasound (LUS) can replace chest x-ray (CXR) when evaluating patients with possible pneumonia. Specifically, we are looking for an overall reduction of CXR when LUS is used first. Our null hypothesis is that LUS cannot replace CXR for diagnosing pneumonia. Our alternate hypothesis is that LUS can replace CXR for diagnosing pneumonia. Our secondary objectives include: (1) a comparison of unscheduled healthcare visits after the index Emergency Department (ED) visit between those subjects who undergo CXR first and those who undergo LUS first, (2) an evaluation of the rate of antibiotic use between the two groups, (3) a comparison of the admission rates, and (4) a comparison of the length of stay in the Emergency Department between the two groups.
Eligibility Criteria
Inclusion Criteria
- All patients who present to the ED with respiratory symptoms suspicious for pneumonia
- In whom the treating physician believes would benefit from diagnostic imaging
Exclusion Criteria
- Patients who arrive at the ED with a previously performed CXR
- Unstable patients with life-threatening injuries who require ongoing resuscitation
Data sourced from ClinicalTrials.gov (NCT01654887). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.