N/A
Completed N=19
Transcranial Magnetic Stimulation Effects on Nicotine Craving
Source: ClinicalTrials.gov NCT01690130 ↗Enrolled (actual)
19
Serious AEs
0.0%
Results posted
Nov 2018
Primary outcomePrimary: the Change From Baseline in Cue Nicotine Craving Rating Score — 64; 46 score on a scale
Summary
The proposed study will measure the change of cortical excitability during nicotine craving and examine the effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on nicotine craving and cue-reactivity among adult regular smokers.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY the Change From Baseline in Cue Nicotine Craving Rating Score |
64; 46 | — |
| SECONDARY the Change From Baseline in Resting Motor Threshold |
42; 44 | — |
Eligibility Criteria
Inclusion Criteria
- Right handed males and females, between the ages of 18 and 50
- Daily smokers who smoke at least 10 cigarettes per day for at least past 1 year
- Mentally capable of reading, writing, giving consent, following instructions
Exclusion Criteria
- history of seizures
- taking medications that lower seizure threshold
- implanted metal devices (e.g., pacemakers, metal plates, wires)
- pregnant
- history of brain surgery or history of loss of consciousness >15 minutes
- any unstable major axis I psychiatric disorder in the past month (e.g. psychotic disorders)
- Current substance use disorders other than nicotine and caffeine use, in the past 30 days
- Any medication (e.g., propranolol) or unstable medical condition that may interfere with psychophysiological (e.g., heart rate) monitoring
Data sourced from ClinicalTrials.gov (NCT01690130). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.