N/A
Completed N=258
Pharmacy-based Interdisciplinary Program for Patients With Chronic Heart Failure
Source: ClinicalTrials.gov NCT01692119 ↗Enrolled (actual)
258
Serious AEs
0.0%
Results posted
Mar 2021
Primary outcomePrimary: Medication Adherence — 91.2; 85.5 percentage of days covered
Summary
The aim of the study is to investigate whether a continuous interdisciplinary intervention improves medication adherence (primary efficacy endpoint) and leads to a reduction of hospitalizations and mortality (primary safety endpoint) in elderly patients with chronic heart failure. The intervention, consisting of regular contacts with the local pharmacy and weekly dosing aids, aims to improve medication adherence and management.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Medication Adherence |
91.2; 85.5 | — |
| PRIMARY Days Lost Due to Unplanned Cardiovascular Hospitalizations or Death of Any Cause |
24.8; 16.5 | — |
Eligibility Criteria
Inclusion Criteria
- Age: 60 years and older
- Chronic heart failure (CHF)
- Stable CHF medication including a diuretic
- Hospitalization for decompensated heart failure within past 12 months OR a value of ≥ 350 pg/mL for BNP or ≥ 1,400 pg/mL for NT-proBNP
- Written informed consent
Exclusion Criteria
- Use of a weekly dosing aid
- Unwillingness or inability to visit a participating pharmacy once a week
- Planned cardiac surgery
- Life-expectancy < 6 months
- Unwillingness or inability to comply with the study protocol (including drug abuse or alcohol dependency)
- Participation in other studies (currently or in the last 4 weeks)
Data sourced from ClinicalTrials.gov (NCT01692119). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.