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N/A N=120 Randomized Double-blind Supportive Care

Postoperatory Analgesia After Total Knee Arthroplasty

PAIN

Enrolled (actual)
120
Serious AEs
0.0%
Results posted
May 2013
Primary outcome: Primary: Postoperatory Analgesia After Total Knee Arthroplasty Comparing Femoral and Sciatic-femoral Block — 2; 2.8; 1.5 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Spinal anesthesia (Other); Femoral nerve block (Other); sciatic nerves block (Other)
Age
Adult, Older Adult · 40+ yrs
Sex
All
Sponsor
Hospital Madre Teresa
Primary completion
Jul 2012

Outcome Measures

OutcomeResultp-value
PRIMARY
Postoperatory Analgesia After Total Knee Arthroplasty Comparing Femoral and Sciatic-femoral Block
2; 2.8; 1.5

Summary

Total knee arthroplasty (TKA) is a worldwide realized procedure, with 600.000 surgeries performed per year in the United States, with a 673% increase estimated until 2030. Functional and pain management improvement is expected in 90% of patients, with 85% of them satisfied after the procedure. Immediate postoperatory pain control is an important aspect to be considered. Patients submitted to TKA endure pain with variations between 40-80 (according to analog visual scale -AVS - which goes from zero to 100) during the immediate postoperatory, with slow decline in the first 24 hours. Pain classified as severe occurs in 60% and moderated in 30% of patients submitted to TKA during this period of time. Therefore adequate pain management allows an earlier rehabilitation, with a higher satisfaction rate and decrease the hospitalization period. A multimodal control of pain can be reached by using non-steroidal anti-inflammatory, COX-2 anti-inflammatory inhibitors, peripheral nerve blocks and intra-articular anesthetics injections and decrease use of opioids given of potential collateral effects. Peripheral blockings are associated to the smallest rate of collateral effects and complications when compared to the spinal anesthesia and analgesia controlled by the patients. Studies comparing the effects of the femoral and sciatic-femoral blocking guided by ultrasonography for the analgesia control after TKA were not found. The objective of this article is to evaluate the effect of femoral and sciatic-femoral block using ultrasonography by the analog visual scale (AVS) of pain in postoperatory of patients submitted to TKA, opioid consumption and complications associated to anesthesics procedures.

Eligibility Criteria

Inclusion Criteria

  • Inclusion criteria were considered: Patients with TKA indication, aged from 40 to 90 years, weight between 50 and 100 kg, body mass index between 18 - 36 and patients classified pre-operatory according to the American Anesthesia Association as ASA I or II.

Exclusion Criteria

  • Non-cooperative patients, with cognitive incapacity to answer pain VAS, neuromuscular or peripheral neuropathies, chronically using opioid or who didn´t want to take part of the study were taken as exclusion criteria.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01700517). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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