N/A N=53 Randomized Double-blind Treatment

Evaluation of Pulse Fibre Supplementation on Obesity and the Metabolic Syndrome

Obesity

Bottom Line

View on ClinicalTrials.gov: NCT01719900 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jan 2020

Primary outcome: Primary: Change in Fat Mass at 12 Weeks — -0.74; 0.42 kg

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Pulse fibre (Dietary_supplement); Control (Dietary_supplement)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: University of Calgary
Primary completion: May 2013

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Fat Mass at 12 Weeks	-0.74; 0.42	—
SECONDARY HbA1c at 12 Weeks	5.68; 5.89	—
SECONDARY Change in Objective Appetite at 12 Weeks	-16; 5	—

Summary

The recent dramatic increase in obesity has been linked to a reduction of dietary fibre intake. We hypothesized that supplementing the diet of overweight and obesity adults with pulse fibre will improve their metabolic status, chiefly defined as greater weight loss. Other metabolic health improvements may include improved glucose control and reduced inflammatory markers.

Eligibility Criteria

Inclusion Criteria

Males and females
Age 18 - 70 years
BMI 25 - 38 kg/m-2
Stable body weight for at least 3 months prior to the study

Exclusion Criteria

Concomitant use of any weight loss medication, diet or exercise regime
Use of corticosteroids, anti-depressants, anti-epileptic medications, lipid lowering medication, diabetes medications
Previous bariatric or other intestinal surgeries
Pregnancy or lactation
Weight loss > 3 kg within preceding 3 months to enrollment
Use of bulk laxatives or probiotics/prebiotics supplements
Antibiotic use in the past month
Clinically significant cardiovascular or respiratory or liver disease

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01719900). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.