Mode
Home
Research
Clinical Trials Drug Pipeline Weekly Digests
Reference
Conditions Medications
Community
Questions
Text Size
Log in / Sign up
N/A N=187 Randomized Treatment

Treating Chronic Pain and Depression in HIV+ Patients in Primary Care Settings

Pain Interference · Depression · Antiretroviral Adherence

Bottom Line

View on ClinicalTrials.gov: NCT01735708 ↗
Enrolled (actual)
187
Serious AEs
32.1%
Results posted
Oct 2022
Primary outcome: Primary: Brief Pain Inventory Interference Scale at 3 Months — 5.03; 4.23 score on a scale — p=0.008

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
HIVPASS (Behavioral); Health Education (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Butler Hospital
Primary completion
Aug 2014

Outcome Measures

OutcomeResultp-value
PRIMARY
Brief Pain Inventory Interference Scale at 3 Months		 5.03; 4.23 0.008 sig
SECONDARY
Brief Pain Inventory Interference Scale at 12 Months		 4.74; 4.95 0.251
SECONDARY
Quick Inventory of Depression Symptoms at 3 Months		 10.35; 10.25 0.844
SECONDARY
Quick Inventory of Depression Symptoms at 12 Months		 10.18; 9.80 0.545

Summary

The purpose of this study is to determine whether participation in the study intervention, which involves collaboration between the study interventionist and the participant's primary care physician, will reduce symptoms of pain and depression in HIV+ patients.

Eligibility Criteria

Inclusion Criteria

  • Chronic Pain (pain duration for at least six months with a mean score of 5 or higher on the BPI Pain Interference Scale)
  • Pain severity of 40 or higher on a Visual Analog Scale (0-100) indicating "worst pain in the last week"
  • At least one trial of PCP-recommended medication (i.e. acetominophen, NSAIDS, skeletal muscle relaxants) judged through interviews with patients and PCPs
  • QIDS score of ≥ 9 (depression severity)
  • Stable dose of an antidepressant, if using, for the previous 2 months
  • Age 18 or older
  • HIV+

Exclusion Criteria

  • Lifetime DSM-IV diagnosis of bipolar disorder, schizophrenia, or other chronic psychotic condition
  • Current DSM-IV diagnosis of substance dependence for alcohol, sedative/ hypnotic drugs, stimulants, or cocaine
  • Suicidal ideation or behavior requiring immediate attention
  • In psychotherapy or in a multidisciplinary pain management program
  • Expected surgery in the next 6 months
  • Pain thought to be due to cancer, infection, or inflammatory arthritis
  • Pregnancy
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01735708). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

Back to search