HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Psychiatry
RCT
Self-help mindfulness and CBT interventions reduce depression and anxiety in distressed students
Mindfulness Apps Help Students Reduce Depression and Anxiety Symptoms
This RCT in 335 distressed university students in China found that self-help mindfulness interventions, with or without CBT, significantly r…
A trial found that online mindfulness programs significantly reduced depression and anxiety symptoms in stressed university students compare…
May 1, 2026
Dermatology
Meta-analysis
Systematic review shows regional differences in HS comorbidity prevalence across North America, Europe, and Asia.
Regional differences in health risks for hidradenitis suppurativa patients
This systematic review and meta-analysis examines the prevalence of hidradenitis suppurativa-associated comorbidities across North America, …
A meta-analysis reveals how hidradenitis suppurativa patients in North America, Europe, and the Middle East/Asia face different odds for dia…
May 1, 2026
Psychiatry
Meta-analysis
Meta-analysis finds NLRP3 inflammasome components upregulated in animal depression models
New research links brain inflammation to depression symptoms in animals
This systematic review and meta-analysis of 170 animals (85 depression model, 85 controls) found that protein and mRNA levels of NLRP3, ASC,…
Scientists found that specific inflammation markers rise in the brains of animals with depression, pointing to a new target for future treat…
May 1, 2026
Diabetes & Endocrinology
RCT
Naltrexone-Bupropion Aids Weight Loss in Overweight Adults With Depression
A New Weight Loss Drug Helps Depression Too
A pooled analysis of 4 double-blind trials found that naltrexone-bupropion (NB-ER) led to significantly greater weight loss than placebo in …
A new weight loss drug helps people lose more weight while keeping their mood stable and safe for those with mild depression.
May 1, 2026
Psychiatry
RCT
Digital mental health intervention reduces anxiety and depression in Chinese high school students
A 12-week digital program reduced depression and anxiety in Chinese high school students
This 12-week randomized controlled trial in 390 Chinese high school students found that a digital mental health literacy intervention integr…
A 12-week digital program reduced depression and anxiety in Chinese high school students compared to controls, offering a scalable solution …
May 1, 2026
Psychiatry
Meta-analysis
Systematic review and meta-analysis of digital technology interventions for cognitive function and mood in older adults
Digital tools may boost brain health in older adults
This systematic review and meta-analysis evaluated digital technology interventions in older adults with cognitive impairment, depression, a…
Using digital technology like apps or online programs may improve thinking skills and mood in older adults, a new analysis suggests.
May 1, 2026
Gastroenterology
Sys. Review
Narrative review discusses pharmacological and lifestyle interventions for type 2 diabetes and psychological health
New hope for diabetes patients struggling with anxiety and depression
This narrative review examines the relationship between type 2 diabetes and conditions such as anxiety, depression, and cognitive impairment…
Diabetes drugs that control blood sugar might also help improve mood and reduce anxiety for patients living with the condition.
Frontiers
Apr 30, 2026
Genetics & Precision Medicine
Cohort
Sex differences in genetic correlation between ischaemic heart disease and depression found in 1.14 million European ancestry individuals
Genetic links between heart disease and depression are twice as strong in women
This review analysis of summary statistics from a sex-stratified genome-wide association study involving 1.14 million European ancestry indi…
Genetic links between heart disease and depression are twice as strong in women. This analysis of 1.14 million people shows why sex matters …
medRxiv
Apr 30, 2026
Oncology
RCT
Mirtazapine and olanzapine reduce anxiety and depression scores in oral cavity cancer patients.
Two Common Pills Ease Cancer Anxiety and Depression
This randomized controlled trial included 144 patients with oral cavity cancer. Both mirtazapine 15 mg/day and olanzapine 5 mg/day significa…
Two well-known antidepressants significantly eased anxiety and depression in oral cancer patients, with mirtazapine showing a slight edge.
Apr 29, 2026
Psychiatry
RCT
Executive function training reduces anxiety and depression in working adults, CBT app improves workplace well-being
Brain Training App Eases Anxiety and Depression at Work
This randomized controlled trial in 228 working adults with mild-to-moderate depression and anxiety compared app-based executive function tr…
A simple brain training app eased anxiety and depression in workers, while a popular CBT app boosted workplace well-being but didn’t reduce …
Apr 28, 2026
Infectious Disease
Sys. Review
Narrative review explores microbiome mechanisms as a promising adjunctive avenue for managing depression, anxiety, bipolar disorder, and schizophrenia.
Gut Bacteria Can Change Your Mood
This narrative review examines how microbiome-driven modulation of neurotransmitters, microbial metabolites, immune activation, and vagal ne…
What if the bacteria in your gut could be quietly shaping how you feel every day — and fixing them could ease anxiety or depression?
Frontiers
Apr 28, 2026
Psychiatry
Cohort
Psychomotor retardation in depression linked to increased Parkinson's risk
Slowed movement in depression signals higher Parkinson disease risk
A retrospective cohort study of 6327 individuals with depression found that those with psychomotor retardation had a 43% higher risk of deve…
Depression with slowed movement links to future Parkinson risk, suggesting physical signs may warn of brain changes years before diagnosis.
medRxiv
Apr 28, 2026