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Phase 4 Completed N=180 Randomized Triple-blind Prevention

Computerized Cognitive Training for Diabetic Elderly Veterans

Source: ClinicalTrials.gov NCT01736124 ↗
Enrolled (actual)
180
Serious AEs
5.6%
Results posted
Feb 2021
Primary outcomePrimary: Diabetes Self-management — 14.9; 15.1 score on a scale
◆ Published Evidence
Emerging
4citations · ~1 / year
Recruitment of Older Veterans with Diabetes Risk for Alzheimer's Disease for a Randomized Clinical Trial of Computerized Cognitive Training.
Journal of Alzheimer's disease : JAD · 2019 · Likely link

Summary

Computerized cognitive training (CCT) is an intervention has improved cognitive functioning in the elderly with and without cognitive impairment. The investigators will study the effect of a CCT program over an active control, "classic" computerized games. The outcomes will be memory and executive functions/attention, diabetes elf-management and adherence to medications, and glycemic and blood pressure control. Non-demented elderly Veterans with diabetes mellitus, who are at high risk for cognitive impairment, will be from the James J. Peters, Bronx, NY and Ann Arbor, MI VAMCs. This novel potential service fits the portfolio of the Quality Enhancement Research Initiative for Diabetes Mellitus (QUERI-DM) for which the Ann Arbor VAMC is a primary center. If successful, the VA National Center for Prevention and MyHeatheVet will collaborate in disseminating results to encourage implementation throughout the VA

Linked Publications

  • Recruitment of Older Veterans with Diabetes Risk for Alzheimer's Disease for a Randomized Clinical Trial of Computerized Cognitive Training.
    Journal of Alzheimer's disease : JAD · 2019 · 4 citations · Likely link

Outcome Measures

OutcomeResultp-value
PRIMARY
Diabetes Self-management
14.9; 15.1
SECONDARY
Medication Adherence
0.11; 0.14
SECONDARY
Memory
0.652; 0.460
SECONDARY
Executive Function/Attention
0.288; 0.327
SECONDARY
Hemoglobin A1c
7.58; 7.50
SECONDARY
Systolic Blood Pressure
129.82; 125.99
SECONDARY
Diastolic Blood Pressure
74.38; 69.77
SECONDARY
Prospective Memory
3.47; 3.40

Eligibility Criteria

Inclusion Criteria

  • 55 years old or above
  • A diagnosis of type 2 diabetes
  • Access to computer and internet
  • Has an informant
  • Self-management score 18 or below

Exclusion Criteria

  • Dementia or prescribed AD medications
  • Major medical, psychiatric, or neurological conditions that affect cognitive performance
  • Severe impairment of vision, hearing or fine motor control necessary for computer operation
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01736124) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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