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N/A N=41,193 Randomized Screening

Strategies and Opportunities to Stop Colon Cancer in Priority Populations

Colorectal Cancer

Enrolled (actual)
41,193
Serious AEs
0.0%
Results posted
Apr 2019
Primary outcome: Primary: FIT Completion — 10.4; 13.9 Model based percentage of participants — p=.05

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Auto Plus (Other)
Age
Adult, Older Adult · 50+ yrs
Sex
All
Sponsor
Kaiser Permanente
Primary completion
Feb 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
FIT Completion
10.4; 13.9 .05
SECONDARY
Any CRC Screening
14.5; 18.3 .02 sig

Summary

Only an estimated 50 million US adults aged 50-75 are up-to-date on colorectal cancer (CRC) screening according to guidelines set by the federal government. CRC is 90% curable with timely detection and appropriate treatment of precancerous polyps; increased screening could reduce incidence by up to 50%. Groups least likely to undergo screening, those with minimal education, low income, low access to health care, recent immigrants or Hispanics, are the same people who frequently receive care at Federally Qualified Healthcare Center's (FQHCs). The use of fecal occult blood tests (FOBT) and fecal immunochemical tests (FIT) is exceedingly low in FQHCs (7-9% of patients in the past year) and far below national averages and target rates. Our results will provide valuable information on how to use electronic health record (EHR) resources to optimize guideline-based screening in FQHC clinics whose patient populations have disproportionately low CRC screening rates. This project, in conjunction with the research team, will use an advisory panel to direct the research activities. The advisory panel will be made up of clinicians, leaders, researchers, and patients. The panel and team will guide the development of materials, the outreach to patients, and the research protocol to best reach FQHC patients who are due for colorectal cancer screening. This project will be conducted in two phases, Phase I is conducting a pilot at two FQHC's, and Phase II is rolling out the intervention to between 20-30 clinics.

Eligibility Criteria

Inclusion Criteria

  • Patients aged 50-74 with no evidence of a colonoscopy within 9 years or fecal testing within 11 months, and no history of colorectal disease will be eligible to receive a mailed FIT.

Exclusion Criteria

  • End Stage Renal Disease (ESRD)
  • Hospice/Nursing Home
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01742065). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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