Phase 4
Completed N=35
A Pilot Comparison of Short-course Nitrofurantoin in Females With Uncomplicated Bacterial Cystitis in the Emergency Department
Uncomplicated Bacterial Cystitis
Source: ClinicalTrials.gov NCT01749605 ↗
Enrolled (actual)
35
Serious AEs
0.0%
Results posted
Apr 2017
Primary outcomePrimary: Number of Participants With Clinical Cure at Day 7 — 13; 12 participants
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
Pilot study to compare the efficacy and safety of 3-day, twice-daily regimens of nitrofurantoin and ciprofloxacin in emergency department (ED) patients presenting with UBC.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With Clinical Cure at Day 7 |
13; 12 | — |
Eligibility Criteria
Inclusion Criteria
- pre-menopausal females
- ages 18-45 years old
- symptoms of a UTI (dysuria, frequency, urgency)
Exclusion Criteria
- Onset of symptoms >7 days prior to the ED visit
- Non-English speaking
- Symptoms of pyelonephritis
- Diabetic
- Indications of sepsis
- Immunocompromised
- Currently using prophylactic antimicrobials
- Medications that could interfere with study drug
- Pregnant
- Lactating
- History of kidney or liver disease
- Vaginal symptoms
- Presence of a urinary catheter
- Treatment for UBC <2 weeks prior to ED visit
- Known allergy to study drug
- Unavailable for follow-up
Data sourced from ClinicalTrials.gov (NCT01749605). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.