N/A
N=487
The SUCCEED Trial of Secondary Stroke Prevention
Stroke · Secondary Stroke Prevention
Bottom Line
View on ClinicalTrials.gov: NCT01763203 ↗Enrolled (actual)
487
Serious AEs
0.0%
Results posted
Nov 2019
Primary outcome: Primary: Systolic Blood Pressure — 133.1; 136.9 mm Hg — p=0.73
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Care Management+Community Health Worker (Behavioral); Usual Care (Behavioral)
- Age
- Adult, Older Adult · 40+ yrs
- Sex
- All
- Sponsor
- University of California, Los Angeles
- Primary completion
- Sep 2018
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Systolic Blood Pressure |
133.1; 136.9 | 0.73 |
| SECONDARY Dyslipidemia |
98.7; 104.1 | 0.77 |
| SECONDARY Percentage of Glycated Hemoglobin (Hemoglobin A1C) |
6.5; 6.6 | — |
| SECONDARY Inflammation: C-reactive Protein |
1.1; 1.2 | 0.002 sig |
| SECONDARY Body Mass Index |
29.5; 29.2 | 0.86 |
| SECONDARY Waist Circumference |
102.9; 101.4 | 0.10 |
| SECONDARY Physical Activity |
1251; 1344 | 0.46 |
| SECONDARY Salt Intake |
181; 168; 27; 34; 33; 44 | 0.011 sig |
| SECONDARY Soda Intake |
107; 102; 99; 99; 35; 45 | 0.47 |
| SECONDARY Fruit and Vegetable Intake |
22; 28; 184; 172; 35; 46 | 0.58 |
| SECONDARY Smoking |
25; 22; 182; 181; 34; 43 | 0.74 |
| SECONDARY Knowledge About Stroke Signs |
95; 65; 69; 75; 28; 40 | 0.0021 sig |
| SECONDARY Knowledge About Stroke Risk Factors |
54; 49; 154; 155; 33; 42 | 0.07 |
| SECONDARY Patient Perception of Quality of Stroke Preventative Care |
126; 91; 30; 42; 36; 55 | 0.32 |
| SECONDARY Vascular Events |
26; 29; 194; 196 | 0.77 |
| SECONDARY Medication Adherence - Global |
148; 150; 31; 27; 2; 1 | 0.20 |
| SECONDARY Medication Adherence - Blood Pressure Medication |
91.6; 89.4 | 0.45 |
| SECONDARY Medication Adherence - Cholesterol Medication |
86.7; 87.1 | 0.93 |
| SECONDARY Medication Adherence - Antithrombotic Medication |
88.5; 89.4 | 0.80 |
| SECONDARY Medication Adherence - Antidepressant Medication |
87.8; 96.2 | 0.25 |
Summary
The purpose of this study is to test a newly-developed outpatient clinic and community-based care intervention called SUCCEED (Secondary stroke prevention by Uniting Community and Chronic care model teams Early to End Disparities) for improving control of stroke risk factors among stroke patients in the Los Angeles County "safety net", and to measure the costs of running such an intervention, relative to usual care.
Eligibility Criteria
Inclusion Criteria
- Patients of Los Angeles County+University of Southern California (LAC-USC), Rancho Los Amigos, Olive View-University of California, Los Angeles (UCLA), or Harbor-UCLA
- Transient ischemic attack (TIA), ischemic stroke or hemorrhagic stroke within the prior 90 days
- English, Spanish, Korean, Mandarin or Cantonese-speaking
- 40 years of age or older
- Capable of giving informed consent (no proxies will be used to obtain consent)
- Systolic blood pressure is 130 mm Hg or greater OR Systolic blood pressure is between 120 mm Hg and 130 mm Hg and there is diagnosed/treated hypertension prior to the stroke or TIA
Exclusion Criteria
- Younger than 40 years
- Systolic Blood Pressure less than 120 mm Hg OR systolic blood pressure is between 120 mm Hg and 130 mm Hg and there is no known history of hypertension prior to the stroke or TIA
- Speaks language other than English, Spanish, Korean, Mandarin, and Cantonese
- Inability to comprehend the study because of communication or cognitive impairments
Data sourced from ClinicalTrials.gov (NCT01763203). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.