N/A
N=17
Arterial Spin Labeling MRI Focal Abnormalities in Refractory Epilepsy
Focal Epilepsy
Bottom Line
View on ClinicalTrials.gov: NCT01772654 ↗Enrolled (actual)
17
Serious AEs
0.0%
Results posted
Mar 2015
Primary outcome: Primary: Intensity of the MRI Signal in the Left Temporal Precentral Zone — 1.06; 1.04 ratio
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Arterial Spin Labeled (ASL) MRI sequence (Device)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Mayo Clinic
- Primary completion
- Nov 2013
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Intensity of the MRI Signal in the Left Temporal Precentral Zone |
1.06; 1.04 | — |
Summary
This study will evaluate a type of Magnetic Resonance Imaging (MRI) sequence called arterial spin labeling (ASL). The investigators hope that ASL can better localize areas of the brain (lesions) that cause epilepsy. This type of MRI does not require contrast, does not use any radiation, and adds on 4 minutes to the routine MRI that is done for patients with epilepsy.
The study hypothesis is that in patients with refractory epilepsy, Arterial Spin Labeling (ASL) MRI will show areas of abnormality in the brain to the same degree as single-photon emission computerized tomography (SPECT) and positron emission tomography (PET) studies.
Eligibility Criteria
Inclusion Criteria
- Medically refractory partial epilepsy.
- Over the age of 18 years.
- Scheduled to have routine epilepsy-protocol MRI after initial evaluation in neurology clinic at Mayo Clinic, Rochester.
- Anticipated to undergo epilepsy monitoring unit (EMU) monitoring.
Exclusion Criteria
- Patients with a generalized epilepsy.
- Under the age of 18 years.
- Unable to undergo MRI imaging of the brain.
Data sourced from ClinicalTrials.gov (NCT01772654). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.