N/A
Completed N=45
Brief Behavioral Intervention for Comorbid Migraine and Depression
Source: ClinicalTrials.gov NCT01775852 ↗Enrolled (actual)
45
Serious AEs
0.0%
Results posted
Sep 2015
Primary outcomePrimary: Mean Change in Hamilton Depression Rating Scale (HAM-D) From Baseline to 12 Week Follow-up — -15.1; -4.3 units on a scale
Summary
The purpose of this research study is to examine whether a one-day group workshop, integrating principles from Acceptance and Commitment Therapy with Migraine Education, will result in improvements in depressive symptoms and functioning impairment in patients with comorbid migraine and depression.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mean Change in Hamilton Depression Rating Scale (HAM-D) From Baseline to 12 Week Follow-up |
-15.1; -4.3 | — |
| SECONDARY Mean Change Score in HDI (Headache Disability Inventory) From Baseline to 12 Weeks. |
-27.9; -10.7 | — |
| SECONDARY Mean Change on Short Form Health Survey (SF-36) From Baseline to 12 Week Follow-up. |
17.0; 7.7 | — |
| SECONDARY Mean Change of World Health Organization Disability Assessment (WHO-DAS) From Baseline to 12-week Follow up. |
-9.1; -.3 | — |
Eligibility Criteria
Inclusion Criteria
- Age 18-75
- 4 to 12 migraines in the previous month
- Major or Minor Depression
- English-speaking
Exclusion Criteria
- Patients with other major psychiatric disorders such as bipolor disorder, schizophrenia, and current illicit drug use.
- Patients with major head injuries.
- Patients with serious medical illnesses.
- Patients who have started a new medication in previous 4 weeks or plan on starting a new medication in the next 4 weeks.
- Patients expressing significant suicidal ideation.
Data sourced from ClinicalTrials.gov (NCT01775852). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.