N/A
N=98
A Web-Based Physical Activity Intervention in Adolescent Survivors of Childhood Cancer
Cancer
Bottom Line
View on ClinicalTrials.gov: NCT01778127 ↗Enrolled (actual)
98
Serious AEs
0.0%
Results posted
May 2015
Primary outcome: Primary: Differences in Change in Daily Average of Moderate and Vigorous Physical Activity (MVPA) Levels Between Groups — -2.58; -2.12; -7.78 minutes — p=0.90
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Activity Monitor (Behavioral); Interactive Website (Behavioral); Educational Materials (Behavioral)
- Age
- Pediatric · 11+ yrs
- Sex
- All
- Sponsor
- St. Jude Children's Research Hospital
- Primary completion
- Apr 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Differences in Change in Daily Average of Moderate and Vigorous Physical Activity (MVPA) Levels Between Groups |
-2.58; -2.12; -7.78 | 0.90 |
| SECONDARY Differences in Change in Cardiovascular Function Between Groups Over 24 Weeks |
-0.21; -1.19; 0.09 | 0.49 |
| SECONDARY Differences in Change in Flexibility Between Groups Over 24 Weeks: Sit and Reach |
-0.71; 2.25; -0.02 | 0.03 sig |
| SECONDARY Differences in Change in Flexibility Between Groups Over 24 Weeks: Active Dorsiflexion |
-1.72; -0.55; -0.32 | 0.49 |
| SECONDARY Differences in Change in Muscular Strength Between Groups Over 24 Weeks: Hand Grip |
1.47; 0.98; 1.00 | 0.61 |
| SECONDARY Differences in Change in Muscular Strength Between Groups Over 24 Weeks: Sit-up |
2.67; 3.29; 2.43 | 0.69 |
| SECONDARY Differences in Change in Muscular Strength Between Groups Over 24 Weeks: Pushup |
2.37; 1.93; 2.27 | 0.78 |
| SECONDARY Differences in Change in Muscular Strength Between Groups Over 24 Weeks: Quadriceps at 60 Degrees/Second |
-4.10; -2.05; -1.91 | 0.83 |
| SECONDARY Differences in Change in Muscular Strength Between Groups Over 24 Weeks: Quadriceps at 120 Degrees/Second |
-6.62; -0.59; 4.16 | 0.44 |
| SECONDARY Differences in Change in Muscular Strength Between Groups Over 24 Weeks: Quadriceps at 180 Degrees/Second |
-0.64; 0.78; 2.55 | 0.17 |
| SECONDARY Differences in Change in Muscular Strength Between Groups Over 24 Weeks: Dorsiflexion at 30 Degrees/Second |
3.94; -3.74; -2.81 | 0.08 |
| SECONDARY Differences in Change in Muscular Strength Between Groups Over 24 Weeks: Dorsiflexion at 60 Degrees/Second |
3.82; -3.00; -2.14 | 0.05 |
Summary
Five year survival following a diagnosis of childhood cancer has reached 83%, making long term health outcomes among survivors an important concern. The growing population of survivors is at an increased risk of physical inactivity and associated adverse health outcomes. Regular physical activity is associated with better cardiovascular and musculoskeletal health. Despite the known benefits of physical activity, nearly half of all childhood cancer survivors do not meet recommended guidelines for physical activity.
Researchers at St. Jude Children's Research Hospital (SJCRH) want to determine if a rewards-based physical activity intervention delivered via an interactive website among young adolescent childhood cancer survivors, aged 11 through 14 years, will increase physical activity levels and improve cardiovascular and musculoskeletal health. The investigators also want to learn if this rewards-based intervention is effective. To achieve this goal the investigators have designed a three-arm prospective, randomized study with two reward-based intervention groups and a control group.
Eligibility Criteria
Inclusion Criteria
- Previously treated for childhood cancer at St. Jude Children's Research Hospital (SJCRH)
- 11 through 14 years of age
- Not undergoing active treatment for cancer
- Medical clearance from participant's attending physician via email
- Does not meet the Centers for Disease Control (CDC) physical activity guidelines. CDC guidelines for children age 11 to 14 are defined as 60 minutes or more per day of physical activity, seven days a week
- Internet access and a computer that has software that is compatible with the study device (Windows XP, Windows Vista, Windows 7, Mac OSX 10.5 and Mac OSX 10.6)
Exclusion Criteria
- Global cognitive impairment (Full Scale Intelligence Quotient < 70) that prevents use of the interactive website
- Pregnant female
- Inability to read and write English
Data sourced from ClinicalTrials.gov (NCT01778127). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.