N/A
N=55
Type 2 Diabetes and Exercise Function in Single Leg Exercises
Type 2 Diabetes
Bottom Line
View on ClinicalTrials.gov: NCT01793909 ↗Enrolled (actual)
55
Serious AEs
0.0%
Results posted
May 2019
Primary outcome: Primary: Change in Muscle Oxygen Saturation — -10.7127; -8.9149; -12.471; -8.7883 percentage
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Single Leg Exercise Training (Other)
- Age
- Adult, Older Adult · 30+ yrs
- Sex
- All
- Sponsor
- University of Colorado, Denver
- Primary completion
- May 2018
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Muscle Oxygen Saturation |
-10.7127; -8.9149; -12.471; -8.7883 | — |
Summary
This study plans to learn more about the effects of type 2 diabetes (T2DM) on exercise blood flow and muscle oxygen uptake. This study will evaluate & compare exercise function during single leg plantar flexion exercise in a total of 45 subjects from the Denver area (15 lean controls, 15 people with T2DM, and 15 overweight control subjects).
Differences between the exercise responses in people with T2DM and healthy people will help further identify the disease process of T2DM and direct future research of treatments and interventions.
Eligibility Criteria
Inclusion Criteria
- Men and women with and without type 2 diabetes
- 30-70 years of age
- Lean and overweight
- Sedentary subjects not participating in a regular exercise program ( 150, diastolic blood pressure (DBP)> 110
- Obstructive pulmonary disease or asthma
- Peripheral neuropathy
- Subjects taking beta blockers, insulin, or Thiazolidinediones (TZD)
- Current or past smoking within the last 2 years
- Anemia
- Control HbA1c > 6, T2DM HbA1c > 10
- Type 1 diabetes
- Any implanted metal in subject's body
Data sourced from ClinicalTrials.gov (NCT01793909). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.