N/A Completed N=45 Randomized Single-blind Treatment

Understanding the Sleep Apnea/Insomnia Interaction

Sleep Apnea Syndromes · Sleep Initiation and Maintenance Disorders

Source: ClinicalTrials.gov NCT01824472 ↗

Enrolled (actual)

Serious AEs

4.4%

Results posted

Aug 2020

Primary outcomePrimary: Insomnia Severity Index Score — -8.2; -7.33; -6.27 score on a scale — p=0.8

Summary

Nearly half of all patients with obstructive sleep apnea have insomnia symptoms, and in some, but not all cases, these insomnia symptoms are caused by the obstructive sleep apnea. The purpose of this study is to find out what type of insomnia symptoms are caused by obstructive sleep apnea and therefore most likely to respond to obstructive sleep apnea treatment with continuous positive airway pressure (also known as CPAP) and if additional treatment with cognitive-behavioral therapy for insomnia is beneficial.

Outcome Measures

Outcome	Result	p-value
PRIMARY Insomnia Severity Index Score	-8.2; -7.33; -6.27	0.8

Eligibility Criteria

Inclusion Criteria

Sleep Apnea
Insomnia
Age >18

Exclusion Criteria

Sedative/psychoactive drug use recently
Other clinically significant sleep disorders
Previous treatment for obstructive sleep apnea (OSA)
Requires oxygen or bilevel PAP therapy
Clinically unstable medical condition
Recent shift work
Significant alcohol use
Other clinically significant causes of insomnia
Illicit drug use
Prescription stimulants
Safety restrictions
Unable to treat sleep apnea with positive airway pressure therapy
Communication barriers
Cognitive impairment

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01824472). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.