Clinical Trial Search

Primary: Model Prediction of Absence/Presence of OSA: Ventilation That Causes an Arousal From Sleep (Varousal) — 5.7; 5.2 L/min — p=0.05

Primary: Number of Subjects With Normalization of Impaired Glucose Tolerance (IGT) — 7; 5 subjects — p=0.57

Primary: CPAP Adherence — 2.8; 3.9 hours per night — p=0.001

Primary: QT Interval (Corrected) Baseline Visit — 453.4 square root of seconds — p=0.73

Primary: Change in Epworth Sleepiness Scale From Baseline to End of Study — -1; -0.5; 1 units on a scale

Primary: Subjective Sleepiness — 11.8; 10.2; 9.9 units on a scale

Primary: Apnea-hypopnea Index (AHI) Per Polysomnography (PSG) at the End of Treatment Period — 4.4; 9.9 AHI (events/hour)

Primary: Change From Baseline in 24-hour Blood Pressure at Months 6 and 12 by Pooled Arms — 1.82; 1.06; 0.59; -0.73 mmHg

Primary: Apnea-hypopnea Index (AHI) at One Year — 35.3; 39.6 events per hour

Primary: Ventilation (Aim 1) — 1.19; 1.14; 1.35; 1.16 fraction of baseline — p=0.001

Primary: Participant Providing Feedback — 26 Participants

Primary: Fat Mass (% of Total Body Mass) — 40.0; 37.7; 38.7; 38.6 percentage of total body mass

Primary: Flow Mediated Dilation — 5.7; 9.5; 7.3 percentage change of vessel diamter — p=0.02

Primary: Objective Sleep Parameters

Primary: The Central Apnea-hypopnea Index — 14.1; 29.9 events per hour

Primary: Apnea Hypopnea Index (AHI) — 2.4 events per hour

Primary: Change in Continuous Glucose Monitoring System Standard Deviation — 0.8; 1.1 mg/dL

Primary: Average Apnea Hypopnea Index Among Different Polysomnography Devices. — 18.4; 25.4; 24.1; 19.2 events per hour

Primary: Left Ventricular Ejection Fraction Improvement — 4.5; -.3 percent change

Primary: Change in Apnea-hypopnea Index (AHI) Outcome Measure in Response to Pioglitazone or Placebo — 35.8; 34.4 AHI events/hour

Primary: Apnea Hypopnea Index (AHI) — 44.77; 47.36; 20.88; 35 events per hour — p=<0.001

Primary: Salivary Cortisol Level

Primary: Change in Total Sleep Time Before and After CPAP Therapy in Obstructive Sleep Apnea Patients — 29 minutes — p=<0.05

Primary: Effect of CPAP on Neurocognitive Function: E/F Function- SWMT-OMD — 0.035; -0.074; 0.072; 0.018 score on a scale — p=0.0074

Primary: Insomnia Severity Index Score — -8.2; -7.33; -6.27 score on a scale — p=0.8

Primary: Change of Daytime Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) Pre-treatment and Post-treatment — -8; -3; -4; -3 mm Hg — p=<0.05

Primary: Relationship Between IOP Fluctuation Pattern With or Without CPAP Therapy in Patients With Moderate to Severe OSAS With or Without POAG — 44.4; 42.2 mVEq/h

Primary: Positive Berlin Questionnaire Indicative of Sleep Disordered Breathing — 1343; 96 participants — p=0.001

Primary: ODI — 24.71; .97 events/hour

Primary: Apnea Hypopnea Index (AHI, Events/Hour of Sleep) — 21.6; 37.9 events/hour of sleep — p=0.56