Phase 2
Completed N=90
Ibuprofen Versus Acetaminophen vs Their Combination in the Relief of Musculoskeletal Pain in the Emergency Setting
Source: ClinicalTrials.gov NCT01827475 ↗Enrolled (actual)
90
Serious AEs
0.0%
Results posted
Dec 2014
Primary outcomePrimary: Pain Severity — 39; 43; 42 mm
Summary
The purpose of this study is to determine whether the combination of ibuprofen and acetaminophen, is more effective than either single agent alone in treating pain from acute musculoskeletal injuries in the emergency department.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Pain Severity |
39; 43; 42 | — |
| SECONDARY Need for Rescue Pain Relief |
11; 10; 5 | — |
Eligibility Criteria
Inclusion Criteria
- Adult patients who presented to the emergency department with pain (a verbal numeric pain score greater than 0 on a scale of 0 to 10 from none to greatest) secondary to an acute musculoskeletal injury of less than 24 hours of duration when one of the study investigators was present were eligible for enrollment
Exclusion Criteria
- Patients who had taken an opioid containing analgesic as well as those with a prior history of allergy or contraindications to ibuprofen or acetaminophen.
Data sourced from ClinicalTrials.gov (NCT01827475). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.