N/A
Completed N=6
Effects of Estrogen Deficiency on Energy Expenditure
Source: ClinicalTrials.gov NCT01846728 ↗Enrolled (actual)
6
Serious AEs
0.0%
Results posted
Nov 2019
Primary outcomePrimary: Brown Adipose Tissue Activity — 3.9; 4.0 Standard uptake value (SUV) — p=0.84
Summary
Menopause is associated with weight gain, but the reasons why are not clear. In this study, the investigators will determine if reducing estrogen levels causes a decrease in the ability of the body to produce heat. If so, this would suggest this is one way that menopause may cause weight gain.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Brown Adipose Tissue Activity |
3.9; 4.0 | 0.84 |
| SECONDARY Cold Induced Thermogenesis |
350; 301 | 0.66 |
| SECONDARY Fat Mass |
24.2; 24.1 | 0.92 |
| SECONDARY Fat Free Mass |
40.3; 40.4 | 0.98 |
| SECONDARY Resting Energy Expenditure |
1382; 1340 | 0.66 |
Eligibility Criteria
Inclusion Criteria
- Body mass index 1 d/wk) over the past 6 months
Data sourced from ClinicalTrials.gov (NCT01846728). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.