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N/A N=100 Randomized Single-blind

Intra-Operative Metrics With CENTURION® and INFINITI® Vision Systems

Cataract

Enrolled (actual)
100
Serious AEs
2.0%
Results posted
Mar 2015
Primary outcome: Primary: Cumulative Dissipated Energy — 4.32; 7.11 percent-seconds

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
CENTURION® Vision System (CVS) (Device); INFINITI® Vision System (IVS) (Device)
Age
Adult, Older Adult · 55+ yrs
Sex
All
Sponsor
Alcon Research
Primary completion
Feb 2014

Outcome Measures

OutcomeResultp-value
PRIMARY
Cumulative Dissipated Energy
4.32; 7.11
PRIMARY
Aspiration (ASP) Fluid Used
46.56; 52.68
SECONDARY
Aspiration Time
151.85; 167.63

Summary

The purpose of this study is to evaluate intra-operative phacoemulsification machine metrics after phacoemulsification with the CENTURION® vision system configuration compared with the INFINITI® vision system configuration.

Eligibility Criteria

Inclusion Criteria

  • Eligible to undergo cataract extraction via phacoemulsification with primary ACRYSOF Intraocular Lens (IOL) implantation;
  • Free of severe disease(s)/condition(s) listed in the "Warnings" and "Precautions" section of implanted ACRYSOF IOL;
  • Willing to undergo second eye surgery within 14 days of first eye surgery;
  • Willing and able to understand/sign a written Informed Consent Document;
  • Willing and able to return for scheduled follow-up examinations;
  • Other protocol-defined inclusion criteria may apply.

Exclusion Criteria

  • Planned multiple procedures at the time of surgery or during the course of the study (eg, LASIK, LRI, etc.);
  • Previous intraocular or corneal surgery of any kind;
  • Poorly dilating pupil;
  • Severe retinal disorders (eg, macular degeneration, proliferative diabetic retinopathy);
  • Corneal disease (eg, herpes simplex, herpes zoster, etc) or retinal detachment;
  • Severe conditions that per Investigator's clinical judgment would increase the operative risk or confound the result of this investigation;
  • Female patients who are pregnant, lactating, or planning to be pregnant during the course of the study;
  • Currently participating in another drug or device clinical trial, or participated in another drug or device clinical trial within 30 days of enrollment into this trial;
  • Other protocol-defined exclusion criteria may apply.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01848288). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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