N/A
N=22
Microcirculatory Perfusion in Patients With Coma After Out-of-hospital Cardiac Arrest
Cardiac Arrest
Bottom Line
View on ClinicalTrials.gov: NCT01850485 ↗Enrolled (actual)
22
Serious AEs
0.0%
Results posted
Jun 2015
Primary outcome: Primary: Microvascular Flow Index (MFI) — 1.7; 1.1 units on a scale
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- microcirculation by SDF and NIRS, in 33 and 36 degrees (Device)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Frisius Medisch Centrum
- Primary completion
- Jan 2013
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Microvascular Flow Index (MFI) |
1.7; 1.1 | — |
| SECONDARY RincStO2 |
44.6; 58.9 | — |
| SECONDARY Fluid Balance After 24 Hours |
1.79; 3.33 | — |
| SECONDARY Inotropes and Vasopressor Dose |
0.00; 0.00 | — |
| SECONDARY Cardiac Index |
2.1; 1.9 | — |
| SECONDARY Lactate |
1.71; 2.78 | — |
| SECONDARY SvO2 |
61.2; 69.4 | — |
Summary
The hypothesis is: In patients after an out of hospital cardiac arrest, treated with therapeutic hypothermia (33°C) will be found significantly more microcirculatory abnormalities, compared to the same group of patients treated with 36°C.
Eligibility Criteria
Inclusion Criteria
- out-of-hospital cardiac arrest
- > 18 years
- informed consent
- ROSC (return of spontaneous circulation) < 4 hours
Exclusion Criteria
- recent maxillofacial surgery
- participation in other clinical trials
Data sourced from ClinicalTrials.gov (NCT01850485). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.