N/A
Completed N=348
Emergency Department (ED) Drug Interaction in Emergency Department Patients
Drug Interactions
Source: ClinicalTrials.gov NCT01859715 ↗
Enrolled (actual)
348
Serious AEs
0.0%
Results posted
May 2016
Primary outcomePrimary: Difference in Clinically Significant Visual Analogue Scale for Pain and Nausea Change Between CYP2D6 Users and Non-users — 7.4; 10.9; -14.0 millimeters
Summary
This study examines how hepatic cytochrome CYP2D6 drug interactions affects the efficacy of oxycodone, hydrocodone, and ondansetron in Emergency Department (ED) patients.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Difference in Clinically Significant Visual Analogue Scale for Pain and Nausea Change Between CYP2D6 Users and Non-users |
7.4; 10.9; -14.0 | — |
| SECONDARY Adverse Drug Events |
0; 0; 0 | — |
Eligibility Criteria
Inclusion Criteria
- self-reported pain or nausea identified by the initial nursing assessment
Exclusion Criteria
- unable to speak English,
- < 18 y.o.,
- previously diagnosed with chronic pain or cyclic vomiting
Data sourced from ClinicalTrials.gov (NCT01859715). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.