Phase 4 N=64 Randomized Treatment

Ultrasound Guided Pain Control Versus Standard Treatment in Emergency Department HIP Fracture Patients

Hip Fracture

Bottom Line

View on ClinicalTrials.gov: NCT01904071 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Apr 2014

Primary outcome: Primary: Pain Score at 30 Minutes — 1.94; 2.05; 5.13 units on a scale — p=<.0001

Study Design & Population

Study type: Interventional
Phase: Phase 4
Interventions: UFNB (Ultrasound guided femoral nerve block) (Procedure); UFIB (Ultrasound Guided Fascia Iliaca Compartment Block) (Procedure); IVMS (IV Morphine) (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Antonios Likourezos
Primary completion: Aug 2010

Outcome Measures

Outcome	Result	p-value
PRIMARY Pain Score at 30 Minutes	1.94; 2.05; 5.13	<.0001 sig
SECONDARY Pain Score at 60 Minutes	2.58; 1.90; 4.40	<.05 sig

Summary

Hip Fracture (HFx) is a painful injury that is often treated in the Emergency Department (ED) with intravenous opiates. However, this class of medications may cause deleterious side effects. An alternative analgesic approach involves regional anesthesia. The investigators attempted to determine (1) whether ultrasound guided peripheral nerve blocks (UPNBs) could be safely performed in an ED setting, (2) whether UPNBs would be more effective than standard treatment in controlling pain from HFx and (3) which of two UPNBs was superior for pain relief. A convenience sample of patients with an isolated HFx and a pain score > 5/10 were enrolled and randomized to one of three arms: (1) Ultrasound guided 3-in-1 femoral nerve block (UFNB), (2) Ultrasound guided fascia iliaca compartment block (UFIB), or (3) IVMS. Patients indicated their pain from 0 (no pain) to 10 (extreme pain).

Eligibility Criteria

Inclusion Criteria

English speaking patients
≥18 years of age
radiographic evidence of hip fracture
Patients must be awake, alert and oriented to time, place and person.
pain score of ≥ 5 in 10 point scale.

Exclusion Criteria

cognitive deficits
allergic to amide-type local anesthetic or morphine
more injuries than just hip fracture.

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Data sourced from ClinicalTrials.gov (NCT01904071). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.