N/A
N=20
Effect of Alveolar Minute Ventilation on Respiratory Gas Heat Content
Ventilation Perfusion Mismatch
Bottom Line
View on ClinicalTrials.gov: NCT01943227 ↗Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Oct 2019
Primary outcome: Primary: Airway Enthalpy — 32; 23 Joules/Minute
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- controlled positive pressure ventilation 9ml/kg tidal volume (Other); controlled positive pressure ventilation 6ml/kg tidal volume (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of California, Davis
- Primary completion
- Mar 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Airway Enthalpy |
32; 23 | — |
Summary
This is a single site, prospective, non-blinded, non-randomized, non-interventional study designed to evaluate the effect of changes in alveolar minute ventilation on the measurement of respiratory heat loss (enthalpy).
Eligibility Criteria
Inclusion Criteria
- age greater than 18 years
- scheduled for an elective surgical procedure with an anticipated duration of more than 2 hours requiring general anesthesia and positive pressure ventilation using an endotracheal tube
- patient status ASA 1, 2 or 3
- no significant cardio-vascular or respiratory disease
- supine surgical position
Exclusion Criteria
- Adults unable to give primary consent
- age less than 18 years
- pregnancy
- prisoners
- pre-existing cardiac or pulmonary disease
- infusion of inotropic drugs
- positive end expiratory pressure (PEEP) requirements >8 cm H2O
- increased intra-abdominal pressure (e.g. planned surgical pneumoperitoneum or ascitis)
- intra-operative patient position other than supine
Data sourced from ClinicalTrials.gov (NCT01943227). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.