N/A
Completed N=18
High Intensity Interval Training in Chronic Stroke
Source: ClinicalTrials.gov NCT01958606 ↗Enrolled (actual)
18
Serious AEs
0.0%
Results posted
Mar 2017
Primary outcomePrimary: Change in Peak Aerobic Capacity (VO2-peak) — 2.2; -1.3 ml/kg/min
Summary
The objective of this study was to compare the effectiveness of high intensity interval training (HIT) and traditional aerobic training for persons with stroke.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Peak Aerobic Capacity (VO2-peak) |
2.2; -1.3 | — |
| SECONDARY Change in Submaximal Aerobic Capacity (VO2 at Ventilatory Threshold) |
4.4; 0.6 | — |
| SECONDARY Change in Gait Velocity (10 Meter Walk Test) |
0.10; 0.02 | — |
| SECONDARY Change in 6-Minute Walk Test |
15; 15 | — |
| SECONDARY Change in Gait Economy (Mean Oxygen Uptake at Comfortable Walking Speed) |
-0.10; -0.01 | — |
| SECONDARY Change in Fastest Treadmill Speed (Steep Ramp Test) |
0.36; 0.07 | — |
| SECONDARY Change in Fractional Utilization |
-36.8; -8.8 | — |
Eligibility Criteria
Inclusion Criteria
- 1) age 35-90 years
- 2) unilateral stroke experienced >6 months prior to enrollment
- 3) able to walk 10m overground with assistive devices as needed and no physical assistance
- 4) able to walk 3 minutes on the treadmill at >.13m/s (0.3mph) with no aerobic exercise contraindications
- 5) stable cardiovascular condition (American Heart Association class B, allowing for aerobic capacity 2)
- 8) lower extremity weight bearing pain >4/10 on visual analogue scale
For the transcranial magnetic stimulation substudy, additional exclusions will also be applied. These include large cerebral infarcts or other structural defects with the potential to increase seizure risk, uncontrolled seizures, metal implants and previous craniotomy.
Data sourced from ClinicalTrials.gov (NCT01958606). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.