Phase 2
N=56
Power Training Post-stroke
Stroke
Bottom Line
View on ClinicalTrials.gov: NCT01970592 ↗Enrolled (actual)
56
Serious AEs
1.8%
Results posted
Mar 2020
Primary outcome: Primary: Gait Speed — 0.51 meters per second
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 2
- Interventions
- POWER training (Behavioral)
- Age
- Adult, Older Adult · 50+ yrs
- Sex
- All
- Sponsor
- VA Office of Research and Development
- Primary completion
- Sep 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Gait Speed |
0.51 | — |
| SECONDARY Muscle Strength |
62 | — |
Summary
Hemiparesis, strictly defined as (muscular) weakness affecting one side of the body, is seen in three-quarters of individuals following stroke. Weakness in this population results from both neural and muscular factors which include, respectively, the ability to activate skeletal muscle as well as the force generating capacity of the muscle. The overall goal is to improve walking in persons post-stroke by training subjects with an intervention that specifically targets existing neural and muscular impairments, thereby facilitating locomotor recovery.
Eligibility Criteria
Inclusion Criteria
- age 50-70,
- stroke within the past 6 to 24 months,
- residual paresis in the lower extremity (Fugl-Meyer Lower Extremity motor score 200 mmHg and diastolic >110 mmHg at rest;
- Previous or current enrollment in a trial to enhance motor recovery;
- Presence of non-magnetic resonance (MR) compatible implants, pregnancy or severe claustrophobia.
Data sourced from ClinicalTrials.gov (NCT01970592). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.