N/A
N=4
A Novel Treatment for Aphasia and Apraxia of Speech : Measurement of Outcomes
Apraxia of Speech · Aphasia
Bottom Line
View on ClinicalTrials.gov: NCT01979159 ↗Enrolled (actual)
4
Serious AEs
0.0%
Results posted
Jun 2019
Primary outcome: Primary: Change in Language Content Production for Treated Stimuli: Effect Sizes (Magnitude of Change From Baseline to Follow-up) — 13.38 units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Combined Aphasia and Apraxia of Speech Treatment (CAAST) (Behavioral)
- Age
- Adult, Older Adult · 21+ yrs
- Sex
- All
- Sponsor
- VA Office of Research and Development
- Primary completion
- Dec 2016
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Language Content Production for Treated Stimuli: Effect Sizes (Magnitude of Change From Baseline to Follow-up) |
13.38 | — |
| PRIMARY Change in Production of Language Content for Untreated Sets - Generalization Measured in Effect Sizes |
7.99 | — |
| SECONDARY Changes in Speech Intelligibility on the Assessment of Intelligibility of Dysarthric Speech |
6.75 | — |
Summary
In order to determine if speech-language therapy has positive effect, reliable measurement tools are required to document outcomes. Currently, there is very limited information concerning the measurement of changes in speech production as a result of treatment for acquired apraxia of speech and aphasia. This study will obtain information concerning the reliability of several speech production measures over time. Thirty persons with chronic aphasia and apraxia of speech will be asked to provide speech samples in response to commonly used assessment tools on three sampling occasions so that the stability of measurements may be examined.
After establishment of appropriate outcome measures, a small, pilot treatment study will be conducted with four participants. The participants will receive a new treatment for aphasia and acquired apraxia of speech and outcomes will be measured relative to speech and language production.
Eligibility Criteria
Inclusion Criteria
- Veterans or non Veterans with aphasia and apraxia of speech who reside in the Salt Lake City region (commutable),
- 12 months or more post stroke or other focal brain injury, no other neurological conditions,
- native English speakers, hearing adequate for experimental task (e.g., pass puretone screening at 35dB at 500, 1K, 2K Hz),
- non linguistic cognition within normal limits
Exclusion Criteria
- less than 12 months post stroke,
- insufficient hearing, insufficient non linguistic cognitive skills,
- neurological conditions other than stroke,
- more than one stroke or brain injury
- unable to attend treatment in the Salt Lake City vicinity
Data sourced from ClinicalTrials.gov (NCT01979159). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.