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N/A Completed N=79 Randomized Supportive Care

Memory Training Versus Yogic Meditation Training in Older Adults With Mild Cognitive Impairment

Source: ClinicalTrials.gov NCT01983930 ↗
Enrolled (actual)
79
Serious AEs
0.0%
Results posted
Oct 2018
Primary outcomePrimary: Cognitive Measures - Hopkins Verbal Learning Test (HVLT) Total Recall Score — 26.02; 25.76; 27.96; 28.81 units on a scale

Summary

The purpose of this pilot study is to test whether 6 months of supervised weekly Kundalini yoga classes and a brief daily meditation homework assignment can improve memory and thinking in older adults with mild memory complaints when compared to weekly classes of memory training with daily homework assignments.

Outcome Measures

OutcomeResultp-value
PRIMARY
Cognitive Measures - Hopkins Verbal Learning Test (HVLT) Total Recall Score
26.02; 25.76; 27.96; 28.81
SECONDARY
Clinical Global Impression Scale
SECONDARY
Geriatric Depression Scale (GDS)
5.7; 7.5; 3.2; 3.9
SECONDARY
Change in Functional Magnetic Resonance Imaging (fMRI) Connectivity
0.011; 0.001; 0.035; 0.001

Eligibility Criteria

Inclusion Criteria

  • Mild cognitive impairment amnestic type
  • Clinical Dementia Rating scale score of 0.5
  • SufficientEnglish proficiency and 8th grade or higher reading level as determined by the word reading subtest of the Wide Range Achievement Test-IV
  • Capacity to provide informed consent.

Exclusion criteria

  • Any current or past psychiatric disorders, or recent unstable medical or neurological disorders
  • Any disabilities preventing their participation in the memory enhancement training (MET) (e.g. severe visual or hearing impairment)
  • Insufficient English proficiency
  • Diagnosis of dementia
  • Mini Mental Health Examination score of 24 and below
  • Psychoactive medications
  • Participation in a psychotherapy that involves cognitive training
  • Do not meet criteria for Mild cognitive impairment subtype
  • Prior or current training in yoga.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01983930). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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