N/A N=79 Randomized Supportive Care

Memory Training Versus Yogic Meditation Training in Older Adults With Mild Cognitive Impairment

Mild Cognitive Impairment

Bottom Line

View on ClinicalTrials.gov: NCT01983930 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Oct 2018

Primary outcome: Primary: Cognitive Measures - Hopkins Verbal Learning Test (HVLT) Total Recall Score — 26.02; 25.76; 27.96; 28.81 units on a scale

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Kundalini yoga and meditation (Behavioral); Memory Training (Behavioral)
Age: Adult, Older Adult · 55+ yrs
Sex: All
Sponsor: University of California, Los Angeles
Primary completion: May 2016

Outcome Measures

Outcome	Result	p-value
PRIMARY Cognitive Measures - Hopkins Verbal Learning Test (HVLT) Total Recall Score	26.02; 25.76; 27.96; 28.81	—
SECONDARY Clinical Global Impression Scale	—	—
SECONDARY Geriatric Depression Scale (GDS)	5.7; 7.5; 3.2; 3.9	—
SECONDARY Change in Functional Magnetic Resonance Imaging (fMRI) Connectivity	0.011; 0.001; 0.035; 0.001	—

Summary

The purpose of this pilot study is to test whether 6 months of supervised weekly Kundalini yoga classes and a brief daily meditation homework assignment can improve memory and thinking in older adults with mild memory complaints when compared to weekly classes of memory training with daily homework assignments.

Eligibility Criteria

Inclusion Criteria

Mild cognitive impairment amnestic type
Clinical Dementia Rating scale score of 0.5
SufficientEnglish proficiency and 8th grade or higher reading level as determined by the word reading subtest of the Wide Range Achievement Test-IV
Capacity to provide informed consent.

Exclusion criteria

Any current or past psychiatric disorders, or recent unstable medical or neurological disorders
Any disabilities preventing their participation in the memory enhancement training (MET) (e.g. severe visual or hearing impairment)
Insufficient English proficiency
Diagnosis of dementia
Mini Mental Health Examination score of 24 and below
Psychoactive medications
Participation in a psychotherapy that involves cognitive training
Do not meet criteria for Mild cognitive impairment subtype
Prior or current training in yoga.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01983930). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.