Combined exercise and diet modestly improves cognition in mild cognitive impairment
Combined exercise and diet plans may help slow thinking problems in older adults with mild memory issues
This systematic review and meta-analysis of 4013 healthy older adults or those with mild cognitive impairment found that combined exercise a…
A large review of over 4,000 people found that mixing exercise with healthy eating might improve overall brain function. However, specific s…
Acupuncture Boosts Cognition in Alzheimer's and Mild Cognitive Impairment
Meta-analysis shows acupuncture improves cognitive function in Alzheimer's and mild cognitive impairment
A meta-analysis of 3362 patients finds acupuncture, alone or with Western medicine, significantly improves cognitive function in Alzheimer's…
A large analysis of 3,362 patients suggests acupuncture may improve cognitive function in Alzheimer's disease and mild cognitive impairment,…
VR and music therapy alleviate anxiety, chronic pain, and cognitive impairment in diverse patients
Virtual reality and music therapy ease anxiety, pain, and brain fog
A scoping review of 34 articles found that integrating Virtual Reality and Music Therapy significantly alleviates symptoms of anxiety, chron…
A review of 34 studies finds VR combined with music therapy significantly reduces anxiety, chronic pain, and cognitive impairment.
SLE linked to 53% higher odds of cognitive impairment in meta-analysis of 7 million
Lupus linked to higher risk of cognitive decline
This meta-analysis of 7 observational studies involving over 7 million participants found that systemic lupus erythematosus (SLE) is signifi…
People with lupus may face 53% higher odds of cognitive impairment, a large analysis finds.
Hypertension history associates with 2.22-fold higher cognitive impairment risk in AF patients
High blood pressure history doubles dementia risk in atrial fibrillation patients
This systematic review and meta-analysis of observational studies found that a history of hypertension is associated with an increased risk …
A history of high blood pressure is linked to a much higher risk of cognitive impairment in people with atrial fibrillation, according to a …
Atractylenolide III shows neuroprotective effects in preclinical CNS disorder models
Atractylenolide III shows promise for brain and nerve injuries in lab models
This narrative review summarizes preclinical evidence that Atractylenolide III exerts neuroprotective effects in models of cognitive impairm…
Atractylenolide III looks like a helpful option for brain and nerve damage in early lab tests, though human trials are needed.
Narrative review suggests music therapy may improve cognition and neuropsychiatric symptoms in cognitive impairment
Music therapy may help minds affected by Alzheimer's and other cognitive conditions
This narrative review examines the role of music therapy for cognitive impairment. The authors suggest that music therapy may improve cognit…
Music therapy might improve thinking and mood for people with Alzheimer's disease, mild cognitive impairment, or Parkinson's-related cogniti…
Systematic review and meta-analysis of retinal biomarkers in frontotemporal dementia and Alzheimer disease
Retinal scans show thinner layers in frontotemporal dementia than Alzheimer disease
This systematic review and meta-analysis synthesized optical coherence tomography data on retinal biomarkers in frontotemporal dementia, Alz…
A new analysis of retinal scans found that people with frontotemporal dementia have thinner eye layers than those with Alzheimer disease or …
Meta-analysis finds higher peripheral Galectin-3 levels in cognitive impairment
People with cognitive impairment had higher blood levels of a protein called Galectin-3 compared to healthy people in this review
This systematic review and meta-analysis compared peripheral Galectin-3 levels between patients with cognitive impairment and healthy contro…
A large review found that people with cognitive impairment have higher levels of a protein called Galectin-3 in their blood. This difference…
tDCS improves global cognition in Alzheimer's and MCI
New meta-analysis finds tDCS improves global cognition in Alzheimer's and mild cognitive impairment
A meta-analysis of 616 patients shows transcranial direct current stimulation significantly improves global cognition in Alzheimer's disease…
A new meta-analysis of 616 patients suggests transcranial direct current stimulation may improve global cognition in Alzheimer's disease and…
Depression linked to higher risk of progression from mild cognitive impairment to Alzheimer's disease and dementia in adults
Depression Linked to Higher Risk of Dementia Progression in Mild Cognitive Impairment
This systematic review and meta-analysis evaluated the association between depression and progression from mild cognitive impairment to Alzh…
A new analysis suggests depression may increase the risk of dementia progression in adults with mild cognitive impairment, though evidence c…
PRKRA gene variants linked to tinnitus and mild cognitive impairment
Gene Variants Linked to Tinnitus and Memory Problems
This RCT of 294 adults with chronic tinnitus from five European clinics found that 15% of those with mild cognitive impairment had rare loss…
Rare gene variants may connect chronic tinnitus with mild cognitive impairment, a new study suggests.
Research across Cognitive Dysfunction
Related studies from across the Cognitive Dysfunction family.
Food insecurity linked to poorer diet and higher obesity risk in older adults
Food Insecurity Linked to Poorer Diet and Obesity in Older Adults
This narrative review synthesizes evidence linking food insecurity and financial hardship to poorer diet quality and higher odds of overweig…
Older adults facing food insecurity eat worse and are more likely to be obese, a review finds.
Younger US men show sharp loneliness increase, older men stable, systematic review finds
Loneliness Linked To Health Risks In Men Across The United States
This systematic review of 30 core studies on US men found no widespread epidemic of loneliness, but younger men (ages 18–29) show a sharp in…
A review of 30 studies finds loneliness in men is linked to depression, heart disease, and higher mortality, with younger men facing a sharp…
Review of ferroptosis role in postoperative cognitive dysfunction in older surgical patients
Aging and surgery may trigger brain cell death in older patients
This narrative review examines the potential role of ferroptosis in postoperative cognitive dysfunction among older surgical patients. The a…
A review suggests aging and surgery might trigger brain cell death in older patients, but scientists are not sure if this process causes the…
Preoperative psychological factors are associated with postoperative cognitive outcomes in older adults
Psychological factors linked to cognitive issues after surgery in older adults
This systematic review and meta-analysis examined preoperative psychological factors in older adults aged 60 years or older.
A large review links preoperative anxiety and stress to worse cognitive outcomes after surgery for older patients.
Meta-analysis finds 24% incidence of cognitive dysfunction after pediatric liver transplant
Nearly 1 in 4 kids face thinking problems after liver transplant
This meta-analysis of 7494 children after liver transplantation reports a pooled incidence of cognitive dysfunction of 24% (95% CI: 19.0%-30…
One in four children develops thinking problems after a liver transplant, with infants facing the highest risk.
Framingham cohort links longitudinal brain atrophy patterns to cognitive decline and AD biomarkers in community-based participants
Brain shrinkage patterns predict Alzheimer's risk in older adults
This community-based cohort study of 300 participants from the Framingham Heart Study analyzed longitudinal brain atrophy patterns using MRI…
A study of 300 older adults found specific brain shrinkage patterns that strongly predict Alzheimer's disease and worse thinking skills.
Living alone not linked to incident dementia but associated with higher institutionalization risk in a cohort of 2,269 individuals
Living Alone Does Not Raise Dementia Risk But Increases Care Needs
This French clinic-based cohort study followed 2,269 individuals with cognitive complaints or mild cognitive impairment for a median of 5 ye…
Living alone does not increase dementia risk, but it does raise the chance of needing nursing home care later.
Bibliometric review of anesthesia-associated postoperative cognitive dysfunction in elderly patients from 2000 to 2024
Why Your Brain Fog After Surgery Might Start in Your Gut
This bibliometric review analyzed 923 publications indexed in the Web of Science Core Collection and PubMed database regarding anesthesia-as…
Understanding how surgery and anesthesia trigger brain inflammation could lead to new ways to prevent memory loss after operations.
Phase 2 RCT of exercise plus ibuprofen for cancer-related cognitive impairment shows mixed cognitive outcomes
Exercise and Common Pain Reliever May Sharpen Thinking During Chemo
This phase 2 randomized controlled trial enrolled 86 patients with cancer receiving chemotherapy reporting cognitive problems.
You’re in the middle of chemotherapy. You love your family, your work, your life.
Menopausal hormone therapy initiation around menopause linked to increased Alzheimer's risk
Hormone Therapy and Dementia: The Truth About Timing
This systematic review and meta-analysis of 213,678 menopausal women found that initiating systemic menopausal hormone therapy (MHT) around …
Many women look to hormone therapy to ease the hot flashes and mood swings of menopause.
Narrative review covers cardiovascular conditions and cognitive decline without reported trial data
Your Heart and Brain Are Talking to Each Other
This narrative review addresses a broad scope of cardiovascular conditions, including stroke, heart failure, atrial fibrillation, and ischem…
Imagine your heart and brain as two best friends who never stop texting each other.
PDE5 inhibitors increased cerebral blood flow in white matter hyperintensity regions in adults with cerebral small vessel disease
An Old Drug Class May Protect the Brain From Silent Damage
This systematic review and meta-analysis evaluated phosphodiesterase-5 inhibitors (sildenafil or tadalafil) versus placebo in 236 adults wit…
Drugs already approved for other conditions may help restore blood flow in a part of the brain that quietly fuels strokes and dementia.
Questions about Mild Cognitive Impairment
Does losing the sense of smell mean mild cognitive impairment will become dementia?
Losing your sense of smell is a warning sign that mild cognitive impairment may progress to dementia, but it does not guarantee it will happen.
Full answer →Can brain shrinkage patterns predict when mild cognitive impairment turns into Alzheimer's disease?
Yes, specific brain shrinkage patterns, especially in the precuneus and fusiform gyrus, can help predict progression from mild cognitive impairment to Alzheimer's disease, but more research is needed.
Full answer →Is replacing plasma with young donor blood safe for people with mild cognitive impairment?
A small pilot study found that replacing plasma with young donor blood is feasible and appears safe in the short term for people with mild cognitive impairment, but larger, longer-term studies are needed.
Full answer →Does type 2 diabetes affect psychological health and cognitive impairment?
Yes, type 2 diabetes is linked to higher risks of depression, anxiety, and cognitive impairment, partly through the gut-brain axis and metabolic effects.
Full answer →All Mild Cognitive Impairment Articles
- Combined exercise and diet modestly improves cognition in mild cognitive impairment
- Acupuncture Boosts Cognition in Alzheimer's and Mild Cognitive Impairment
- VR and music therapy alleviate anxiety, chronic pain, and cognitive impairment in diverse patients
- SLE linked to 53% higher odds of cognitive impairment in meta-analysis of 7 million
- Hypertension history associates with 2.22-fold higher cognitive impairment risk in AF patients
- Atractylenolide III shows neuroprotective effects in preclinical CNS disorder models
- Narrative review suggests music therapy may improve cognition and neuropsychiatric symptoms in cognitive impairment
- Systematic review and meta-analysis of retinal biomarkers in frontotemporal dementia and Alzheimer disease
- Meta-analysis finds higher peripheral Galectin-3 levels in cognitive impairment
- tDCS improves global cognition in Alzheimer's and MCI
- Depression linked to higher risk of progression from mild cognitive impairment to Alzheimer's disease and dementia in adults
- PRKRA gene variants linked to tinnitus and mild cognitive impairment
- Repetitive transcranial magnetic stimulation shows promise for improving cognition and executive function in patients with mild cognitive impairment
- AI-assisted PET radiomics improves Alzheimer's diagnosis over conventional methods in meta-analysis
- Systematic review and meta-analysis shows computerized cognitive training improves mild cognitive impairment
- Systematic review and meta-analysis of Zingiberaceae-derived interventions for memory-related outcomes in adults
- Ashwagandha supplementation shows cognitive and physical benefits in adults
- Systematic review of 88 observational studies on missing data reporting in T2DM-MCI research
- Meta-analysis finds combined exercise and tDCS improves cognition in older adults
- Systematic review and meta-analysis reports 36.6% cognitive impairment prevalence in coronary heart disease patients
- Narrative review links soil contaminants and micronutrient depletion to hypertension, atherosclerosis, and neurodegenerative processes
- ICU CogHab cognitive rehabilitation feasibility study in ICU survivors with cognitive impairment
- Systematic review and meta-analysis of digital technology interventions for cognitive function and mood in older adults
- Pilot study assesses safety and feasibility of young donor plasma replacement in mild cognitive impairment
- Narrative review discusses pharmacological and lifestyle interventions for type 2 diabetes and psychological health
- Diabetes and social support associations with cognitive impairment in elderly schizophrenia inpatients
- Framingham cohort links longitudinal brain atrophy patterns to cognitive decline and AD biomarkers in community-based participants
- Review of cross-sectional EEG study on 32-Hz stimulation in Alzheimer's disease and mild cognitive impairment
- Lower MAMC and higher MIS associated with cognitive impairment in maintenance hemodialysis patients
- Network meta-analysis finds PUFA supplements may benefit cognition in mild cognitive impairment
- Narrative review discusses postoperative care strategies for older adults with hip fracture and cognitive impairment
- Review of EEG microstate analysis shows high diagnostic accuracy for distinguishing neuropsychiatric symptoms from cognitive impairment
- Olfactory decline associated with conversion to mild cognitive impairment and dementia in unimpaired adults
- AI-driven home cognitive program improves global cognition in older adults with MCI
- Cross-sectional study observes differences in cardiovascular regulatory responses in mild cognitive impairment
- Meta-analysis links digital exclusion to functional decline and dementia in older adults
- Review of MRI radiomic features aids Alzheimer's disease classification and progression modeling in 382 participants
- Meta-analysis finds trivial cognitive effects of amyloid antibodies in mild Alzheimer's disease
- CABG linked to higher impaired cognition risk in older CAD patients with APO genotype variation
- Poor multidimensional sleep health associated with cognitive impairment in middle-aged adults
- Review of bilingualism effects on naming performance in Catalan-Spanish speakers with cognitive impairment
- Virtual reality cognitive training shows benefit on cognition in older adults with mild cognitive impairment
- REDDI pipeline improves balanced accuracy for classifying MCI, MS, Parkinson's, and ALS using MEG data
- In older in-patients with type 2 diabetes and cognitive impairment, CGM showed superior glucose metrics compared to point-of-care tests
- Resting-state facial expressions differ significantly between older adults with mild cognitive impairment and healthy controls
- Hearing aid use associated with improved cognition and reduced cognitive impairment risk in older adults
- TCM-NPIs show cognitive score improvements in MCI patients in network meta-analysis
- Meta-analysis of 7,048 first-time stroke patients across six countries reports post-stroke cognitive impairment incidence rates
- Retrospective study links coronary artery disease to EEG connectivity changes in elderly patients with hypertension
- Transcutaneous auricular vagus nerve stimulation shows modest cognitive improvements in mild cognitive impairment and post-stroke cognitive impairment
- Spatial coupling of enlarged perivascular spaces and white matter lesions observed across Alzheimer's disease continuum stages
- Systematic review suggests beef consumption may improve attention and memory in young adult females with iron deficiency
- Nurse-led music intervention shows preliminary benefit for cognitive impairment in colorectal cancer patients
- Qigong shows large effect on subjective cognitive function in cancer survivors in meta-analysis
- Self-management and glycemic control linked to lower MCI risk in rural elderly with type 2 diabetes
- Plant-based diet adherence associated with lower cognitive impairment risk in meta-analysis
- Meta-analysis finds distinct fMRI activation patterns in MCI and Alzheimer's disease during cognitive tasks