N/A N=48 Randomized Double-blind Treatment

Amplitude and Rate of Intrinsic Feedback During Treadmill Training for Parkinson's Disease

Parkinson's Disease · Treadmill

Bottom Line

View on ClinicalTrials.gov: NCT01987557 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jun 2015

Primary outcome: Primary: Motor Section of the Unified Parkinson's Disease Rating Scale (UPDRS-III) — 23.35; 22.96; 22.46; 18.81 units on a scale (0-4)

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: rate group (Behavioral); magnitude treadmill group (Behavioral); regular treadmill walking (Behavioral)
Age: Adult, Older Adult · 40+ yrs
Sex: All
Sponsor: Wilfrid Laurier University
Primary completion: Aug 2014

Outcome Measures

Outcome	Result	p-value
PRIMARY Motor Section of the Unified Parkinson's Disease Rating Scale (UPDRS-III)	23.35; 22.96; 22.46; 18.81; 20.69; 20.92	—
SECONDARY Spatiotemporal Aspects of Gait	—	—
SECONDARY Static Posturography (Balance/Postural Control)	—	—

Summary

Treadmill training has been shown to be beneficial for reducing motor symptoms of Parkinson's disease (PD). The mechanisms for the therapeutic effects of treadmill training remain unknown. However, specific types of intrinsic feedback generated from muscle spindles (detect changes in length of muscle) and golgi tendon organs (detect muscle force) seem to be an important factor for achieving the reductions in motor scores. This study will compare a treadmill program that generates a high rate of intrinsic feedback to a treadmill program focused on generating a high magnitude of intrinsic feedback.

Eligibility Criteria

Inclusion Criteria

diagnosis of Parkinson's disease
must be able to walk unassisted for 10 metres

Exclusion Criteria

cardiovascular disease/history of stroke
Dementia
lower body injury that would be worsened by repetitive walking

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Data sourced from ClinicalTrials.gov (NCT01987557). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.