N/A
Completed N=48
Amplitude and Rate of Intrinsic Feedback During Treadmill Training for Parkinson's Disease
Parkinson's Disease · Treadmill
Source: ClinicalTrials.gov NCT01987557 ↗
Enrolled (actual)
48
Serious AEs
0.0%
Results posted
Jun 2015
Primary outcomePrimary: Motor Section of the Unified Parkinson's Disease Rating Scale (UPDRS-III) — 23.35; 22.96; 22.46; 18.81 units on a scale (0-4)
Summary
Treadmill training has been shown to be beneficial for reducing motor symptoms of Parkinson's disease (PD). The mechanisms for the therapeutic effects of treadmill training remain unknown. However, specific types of intrinsic feedback generated from muscle spindles (detect changes in length of muscle) and golgi tendon organs (detect muscle force) seem to be an important factor for achieving the reductions in motor scores. This study will compare a treadmill program that generates a high rate of intrinsic feedback to a treadmill program focused on generating a high magnitude of intrinsic feedback.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Motor Section of the Unified Parkinson's Disease Rating Scale (UPDRS-III) |
23.35; 22.96; 22.46; 18.81; 20.69; 20.92 | — |
| SECONDARY Spatiotemporal Aspects of Gait |
— | — |
| SECONDARY Static Posturography (Balance/Postural Control) |
— | — |
Eligibility Criteria
Inclusion Criteria
- diagnosis of Parkinson's disease
- must be able to walk unassisted for 10 metres
Exclusion Criteria
- cardiovascular disease/history of stroke
- Dementia
- lower body injury that would be worsened by repetitive walking
Data sourced from ClinicalTrials.gov (NCT01987557). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.