Phase 4
Completed N=180
A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye Symptoms
Dry Eye Syndromes · Cataract
Source: ClinicalTrials.gov NCT02028754 ↗
Enrolled (actual)
180
Serious AEs
0.0%
Results posted
Apr 2014
Primary outcomePrimary: Tear Break-Up Time (TBUT) in the Study Eye — 8.5; 6.6 Seconds
Summary
This study will evaluate the effect of sodium carboxymethylcellulose eye drops in the treatment of dry eye after cataract surgery.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Tear Break-Up Time (TBUT) in the Study Eye |
9.0; 6.7 | — |
| SECONDARY Fluorescein Staining Score in the Study Eye |
2.0; 1.8; 1.1; 1.2 | — |
| SECONDARY Lissamine Green Staining Score in the Study Eye |
2.9; 2.6; 2.1; 2.3 | — |
| SECONDARY Results of Schirmer I Test With Anesthetics in the Study Eye |
11.8; 12.5; 12.7; 12.6 | — |
| SECONDARY Ocular Surface Disease Index (OSDI) Questionnaire Score in the Study Eye |
15.6; 18.1; 12.7; 14.2 | — |
| SECONDARY Subjective Symptom Total Score in the Study Eye |
6.1; 6.4; 5.1; 5.6 | — |
Eligibility Criteria
Inclusion Criteria
- Diagnosis of age-related cataract in the study eye
- Scheduled for cataract surgery and lens implant
Exclusion Criteria
- Diagnosis of ocular surface disease or glaucoma
- Ocular surgery in the past 3 months
- Wearing a corneal contact lens in the study eye
Data sourced from ClinicalTrials.gov (NCT02028754). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.