N/A
N=108
Transversus Abdominis Plane Block Versus Local Anesthetic Infiltration for Pain Control in the Abdominal Surgery
Postoperative Pain
Bottom Line
View on ClinicalTrials.gov: NCT02029755 ↗Enrolled (actual)
108
Serious AEs
0.0%
Results posted
Jun 2015
Primary outcome: Primary: Pain Score (NRS: Numerical Rating Scale) — 4.50; 4.81; 4.17 units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- transversus abdominis plane block (Procedure); local infiltration (Procedure); Patient controlled analgesia (Procedure)
- Age
- Adult, Older Adult · 20+ yrs
- Sex
- All
- Sponsor
- Taipei Medical University Hospital
- Primary completion
- Apr 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Pain Score (NRS: Numerical Rating Scale) |
4.50; 4.81; 4.17 | — |
| PRIMARY Opioid Consumption |
27.69; 28.33; 21.53 | — |
| SECONDARY Sedation Scale |
— | — |
| SECONDARY Nausea and Vomiting Categorical Score |
— | — |
| SECONDARY Rescue Analgesic Use |
— | — |
| SECONDARY Rescue Antiemetics Use |
— | — |
| SECONDARY Time to the First Request of Analgesics |
— | — |
| SECONDARY Pruritus |
— | — |
| SECONDARY Quality of Recovery 40 |
— | — |
| SECONDARY Heart Rate Variability |
— | — |
| SECONDARY Time to Flatus |
— | — |
| SECONDARY Length of Hospital Stay |
— | — |
| SECONDARY Number of Participants With Intervention-related Complication |
— | — |
Summary
Postoperative analgesia is an important part of the anesthetic care. According to the recent studies, multimodal analgesia can provide better analgesia & patient satisfaction with fewer side effect. For example, combining intravenous, intramuscular or oral analgesics with transversus abdominis plane (TAP) block or local anesthetic (LA) infiltration as the multimodal analgesia, can furnish a more effective pain control after the abdominal surgery.
For abdominal surgery, both local infiltration and TAP block target on relieving somatic pain. Local anesthetic wound infiltration is easy to perform with low risk. As the advancement of ultrasound technology, performing the TAP block also becomes easier, safer and more accurate. But whether LA infiltration or TAP block is better for the multimodal analgesia regimen remains unclear.
This study is to compare the postoperative pain score, opioid consumption, side effects, and quality of recovery between these two analgesic methods in patients undergoing abdominal surgery. The investigators hypothesized that TAP block may be more effective than LA infiltration as a part of the multimodal analgesia, and can improve the recovery after the abdominal surgery.
Eligibility Criteria
Inclusion Criteria
- Adult (20~65y/o)
- American Society of Anesthesiologists (ASA) physical status I~II
- Patients scheduled for regular abdominal surgery under general anesthesia
Exclusion Criteria
- ASA physical status ≥ 3
- Allergy to morphine or local anesthetics
- Morphine tolerance
- Drug abuse or addiction
- Bleeding tendency
Data sourced from ClinicalTrials.gov (NCT02029755). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.