Phase 4
N=60
TAP Block With Plain Bupivacaine Versus Wound Infiltration With Exparel for Postoperative Pain Management
Postoperative Pain
Bottom Line
View on ClinicalTrials.gov: NCT02074709 ↗Enrolled (actual)
60
Serious AEs
0.0%
Results posted
Dec 2014
Primary outcome: Primary: Postoperative Pain Score on Coughing at 6 hr — 5.28; 3.59 units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 4
- Interventions
- Plain bupivacaine (Drug); Liposomal bupivacaine (Drug)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- Female
- Sponsor
- University of Texas Southwestern Medical Center
- Primary completion
- Sep 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Postoperative Pain Score on Coughing at 6 hr |
5.28; 3.59 | — |
Summary
In this randomized, controlled, observer-blinded study we plan to evaluate pain relief after ultrasound-guided transversus abdominis plane (TAP) block using bupivacaine and wound infiltration using liposomal bupivacaine in patients undergoing abdominal hysterectomy.
Eligibility Criteria
Inclusion Criteria
- Female
- ASA physical status 1-3
- Scheduled for open abdominal hysterectomy
- Age 18-80 years old
- Able to participate personally or by legal representative in informed consent in English or Spanish
Exclusion Criteria
- History of relevant drug allergy
- Age less than 18 or greater than 80 years
- Chronic opioid use or drug abuse
- Significant psychiatric disturbance
- Inability to understand the study protocol
- Refusal to provide written consent
Data sourced from ClinicalTrials.gov (NCT02074709). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.