Phase 4
Completed N=60
TAP Block With Plain Bupivacaine Versus Wound Infiltration With Exparel for Postoperative Pain Management
Source: ClinicalTrials.gov NCT02074709 ↗Enrolled (actual)
60
Serious AEs
0.0%
Results posted
Dec 2014
Primary outcomePrimary: Postoperative Pain Score on Coughing at 6 hr — 5.28; 3.59 units on a scale
Summary
In this randomized, controlled, observer-blinded study we plan to evaluate pain relief after ultrasound-guided transversus abdominis plane (TAP) block using bupivacaine and wound infiltration using liposomal bupivacaine in patients undergoing abdominal hysterectomy.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Postoperative Pain Score on Coughing at 6 hr |
5.28; 3.59 | — |
Eligibility Criteria
Inclusion Criteria
- Female
- ASA physical status 1-3
- Scheduled for open abdominal hysterectomy
- Age 18-80 years old
- Able to participate personally or by legal representative in informed consent in English or Spanish
Exclusion Criteria
- History of relevant drug allergy
- Age less than 18 or greater than 80 years
- Chronic opioid use or drug abuse
- Significant psychiatric disturbance
- Inability to understand the study protocol
- Refusal to provide written consent
Data sourced from ClinicalTrials.gov (NCT02074709). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.