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N/A N=210 Randomized Triple-blind Basic Science

Effects of Maternal Interpretation Biases on Child Anxiety and Related Responses

Anxiety Disorders

Enrolled (actual)
210
Serious AEs
0.0%
Results posted
Feb 2020
Primary outcome: Primary: Word Sentence Association Paradigm — 0.37; 0.52; 0.27 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Positive Interpretation Bias Training (Other); Neutral Interpretation Bias Training (Other)
Age
Pediatric · 8+ yrs
Sex
All
Sponsor
University of Houston
Primary completion
Apr 2018

Outcome Measures

OutcomeResultp-value
PRIMARY
Word Sentence Association Paradigm
0.37; 0.52; 0.27
PRIMARY
Maternal Anxious Behavior Coded by Independent Observers.
1.43; 1.70; 2.02

Summary

The purpose of this study is to expand our understanding of the intergenerational transmission of cognitive risk for childhood anxiety disorders by examining whether changes in maternal interpretations of situations result in changes in child interpretations and child anxiety.

Eligibility Criteria

Inclusion Criteria

  • Children ages 8-12
  • Children with primary diagnosis of anxiety disorder
  • Mothers with clinical levels of anxiety symptoms on the Depression, Anxiety, and Stress Scales (DASS; Lovibond & Lovibond, 1995)

Exclusion Criteria

  • Physical disability impairing ability to use a computer
  • Intelligence Quotient <80
  • Reading comprehension and fluency composite <75
  • Concurrent primary diagnosis of any non-anxiety disorder
  • Currently receiving psychological or pharmacological treatment for anxiety
  • Danger to self/others
  • Non-English speaking child/parent
  • Maternal current involvement in cognitive-behavioral therapy
  • Maternal changes in pharmacological treatment in the 12 weeks prior to enrollment.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02095340). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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