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N/A N=200 Randomized Single-blind Treatment

Randomized Controlled Trial of a Patient Activation Tool in Pediatric Appendicitis (Antibiotics Alone vs. Appendectomy)

Appendicitis · Children

Enrolled (actual)
200
Serious AEs
0.0%
Results posted
Jul 2019
Primary outcome: Primary: Decision Self-Efficacy Scale — 100; 100 units on a scale — p=0.03

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Patient Activation Tool (Other)
Age
Pediatric · 7+ yrs
Sex
All
Sponsor
Peter Minneci
Primary completion
Aug 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Decision Self-Efficacy Scale
100; 100 0.03 sig
PRIMARY
PedsQL 3.0 Healthcare Satisfaction Generic Module (Parent Report)
98.3; 99.0 .27
PRIMARY
Disability Days
5; 6 .67
SECONDARY
Patient Activation Measure (PAM)
91; 100 .17
SECONDARY
Number of Participants Readmitted
15; 15 .84
SECONDARY
PedsQL Pediatric Quality of Life Inventory and PedsQL Family Impact Module Scales
88.0; 88.0 .99

Summary

The purpose of this study is to determine if a patient activation tool (PAT) can improve decision making and patient centered outcomes in pediatric patients with appendicitis and their caregivers choosing between antibiotics alone and appendectomy.

Eligibility Criteria

Inclusion Criteria

  • Age : 7-17 years
  • Ultrasound (US) or Computed Tomography (CT) confirmed early appendicitis:
  • US: hyperemia, <1.1 cm in diameter, compressible or non-compressible, no abscess, no fecalith, no phlegmon
  • CT: hyperemia, fat stranding, <1.1 cm in diameter, no abscess, no fecalith, no phlegmon
  • White Blood Cell count < 18,000
  • C-reactive Protein<4 (if obtained)
  • Focal abdominal pain </= 48 hours prior to receiving antibiotics

Exclusion Criteria

  • Positive urine pregnancy test
  • Other significant co-morbidities:
  • cardiovascular disease
  • malignancy
  • pulmonary disease
  • severe developmental delay
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02110485). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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