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Orthopedics & Sports Medicine
Cohort
Peripheral blood inflammatory markers associated with complicated acute appendicitis in retrospective cohort study
Blood marker helps predict complicated appendicitis severity
This retrospective study of 533 patients evaluated the diagnostic value of peripheral blood composite inflammatory markers for identifying c…
Doctors may soon use a specific blood marker to tell if your appendicitis is simple or turning into a much more serious complication.
Frontiers
Apr 30, 2026
Infectious Disease
Meta-analysis
Antibiotic therapy versus appendectomy showed no difference in one-year complication rates for adults with imaging-confirmed acute appendicitis.
Is taking antibiotics or surgery better for your appendix, and what does the data really show?
This meta-analysis of individual patient data from randomized controlled trials included 2,101 adults with imaging-confirmed acute appendici…
Choosing antibiotics over surgery for your appendix carries similar risks for most, but a specific stone makes complications much more likel…
Apr 9, 2026
Orthopedics & Sports Medicine
Cohort
NLR, SII, and appendiceal diameter combination shows diagnostic accuracy for complicated appendicitis
Can simple blood tests and a scan help doctors spot a more serious appendicitis?
A retrospective single-center diagnostic cohort study of 207 patients with pathologically confirmed appendicitis found that combining neutro…
Combining two simple blood markers with a scan width helps doctors spot serious appendicitis about 87% of the time before surgery.
Frontiers
Apr 3, 2026
Infectious Disease
RCT
Antibiotics for Appendicitis: 37.8% Recurrence, 44.3% Appendectomy at 10 Years
Is Antibiotic Treatment for Appendicitis a Safe Long-Term Option?
In a 10-year follow-up of the APPAC trial, 37.8% of patients treated with antibiotics for uncomplicated appendicitis experienced recurrence,…
Nearly half of patients treated with antibiotics for appendicitis avoided surgery entirely over 10 years, though about 38% experienced a rec…
JAMA
Mar 27, 2026