N/A
Completed N=33
Transcranial Direct Current Stimulation (tDCS) As A Treatment For Cigarette Craving and Cognitive Deficits in Schizophrenic
Schizophrenia · Cognition · Cigarette Smoking
Source: ClinicalTrials.gov NCT02128919 ↗
Enrolled (actual)
33
Serious AEs
0.0%
Results posted
Aug 2017
Primary outcomePrimary: Change From Baseline in Cigarette Craving — 14.40; 11.00 Units on QSU-Brief Scale
Summary
This is a study of the effects of tDCS on smoking, craving for cigarettes, cognition, and psychiatric symptoms in schizophrenic patients who are current smokers or have a history of regular cigarette smoking. It assesses smoking with CO monitoring, nicotine and nicotine levels, and craving with QSU scale and response to craving slides. Cognition is measured by MCCB, symptoms are measured by PANSS and hallucination scale.
This is a double-blind sham-controlled study with active tDCS 2ma or 20 minutes over 5 days, and sham tDCS for 40 seconds on each sham occasion.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change From Baseline in Cigarette Craving |
14.40; 11.00 | — |
| SECONDARY Change From Baseline in Cognitive Performance |
3.47; -0.85; 4.04; -3.29; 4.25; -1.91 | — |
Eligibility Criteria
Inclusion Criteria
- Diagnosis of schizophrenia spectrum disorder History of cigarette smoking
Exclusion Criteria
- Seizure disorder or current treated neurological illness Current Acute exacerbation of psychotic state
Data sourced from ClinicalTrials.gov (NCT02128919). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.