Phase 4
Completed N=45
The Effect of Thoracic Epidural Anesthesia With Different Block Level on Propofol Induction
Target Controlled Infusion (TCI) · Thoracic Epidural Anesthesia · Block Level · Gastrointestinal Surgery
Source: ClinicalTrials.gov NCT02135016 ↗
Enrolled (actual)
45
Serious AEs
0.0%
Results posted
Aug 2014
Primary outcomePrimary: The Effect-site Concentration of Propofol — 1.51; 1.99; 2.68 µg/ml
Summary
It is a prospective, randomized, placebo-controlled study to investigate the effect of TEA with different block level on propofol concentration during general anesthesia induction.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Effect-site Concentration of Propofol |
1.51; 1.99; 2.68 | — |
| SECONDARY The Bispectral Index |
95.4; 95.4; 95.7; 85.3; 85.1; 94.5 | — |
| SECONDARY The Mean Blood Pressure |
95.4; 95.1; 95.9; 85.9; 83.7; 95.5 | — |
| SECONDARY The Heart Rate |
71.4; 72.8; 71.3; 69.8; 69.2; 71.3 | — |
| SECONDARY The Block Level of Epidural Anesthesia |
6.5; 4.2; 0 | — |
Eligibility Criteria
Inclusion Criteria
- American Society of Anesthesiologists (ASA) I-II physical status,
- aged 40-60 yr,
- BMI 19-25 kg/m2,
- undergoing elective gastrointestinal surgery
Exclusion Criteria
- patients with cardiovascular or neurological disease, drug or alcohol abuse and absolute contraindications for neuraxial blockade.
Data sourced from ClinicalTrials.gov (NCT02135016). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.