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N/A N=198

LifeVest Trends Validation Protocol

Heart Failure

Enrolled (actual)
198
Serious AEs
2.5%
Results posted
Aug 2020
Primary outcome: Primary: Distance Traveled in Six Minute Walk Test — 306; 296 meters

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
Trends-equipped LifeVest 4000 (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Zoll Medical Corporation
Primary completion
Dec 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Distance Traveled in Six Minute Walk Test
306; 296
SECONDARY
Compliance With Completing 6MWT Through a Wearable Defibrillator.
79
SECONDARY
Observe Compliance With Answering Questions Regarding Health Through a Wearable Defibrillator.
93

Summary

This study will evaluate the accuracy of data on body position, daily activity, heart rate, 6-minute walk test, and a health survey collected by the wearable cardioverter defibrillator (WCD).

Eligibility Criteria

Inclusion Criteria

  • Symptomatic heart failure (i.e., New York Heart Association (NYHA) class II or higher)
  • Evidence of a prior Myocardial Infarction (MI) or dilated cardiomyopathy
  • Ejection fraction of 35% or less at the start of WCD use
  • Anticipated to need a WCD for three months or more
  • At least 18 years of age (over the legal age of providing consent)

Exclusion Criteria

  • Use of an implantable cardioverter defibrillator (ICD), recent removal of an ICD, or planned use of an ICD within the next three months
  • Need for an assistive device for ambulation (wheelchair, walker, or cane)
  • Use of a unipolar pacemaker
  • Physical or mental conditions that prevent interaction with or wearing of the device
  • Advanced directive prohibiting resuscitation
  • Pregnancy
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02149290). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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