N/A N=12 Randomized Other

Impact of Breakfast Composition on Glycemic and Incretin Responses in Individuals With Type 2 Diabetes

Type 2 Diabetes

Bottom Line

View on ClinicalTrials.gov: NCT02180646 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jan 2017

Primary outcome: Primary: Plasma Glucose Level Post-meal (AUC [0-4]) — 28426; 33911 min*pg/ml

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: High protein breakfast (Other); High carb breakfast (Other)
Age: Adult · 21+ yrs
Sex: All
Sponsor: University of Missouri-Columbia
Primary completion: Apr 2013

Outcome Measures

Outcome	Result	p-value
PRIMARY Plasma Glucose Level Post-meal (AUC [0-4])	28426; 33911	—
SECONDARY Post-meal Level of Glucose-dependent Insulinotropic Peptide (GIP) (AUC)	15156; 14620	—

Summary

This study examined the effect of a high protein or high carbohydrate breakfast on the glucose and insulin response following the breakfast meal, as well as the subsequent response following the lunch meal.

Eligibility Criteria

Inclusion Criteria

21-55 y of age
body mass index (BMI) between 30-40 kg/m2
weight stable for the prior 6 months
non-smokers
minimal alcohol consumption (< 2 drinks per day)
type 2 diabetic (diagnosed ≥ 2 y)
a fasting glucose level above 120 mg/dL
HbA1c between 6.5-9.0%

Exclusion Criteria

insulin
β-blockers
GLP-1 agonists (e.g. exenatide)
dipeptidyl peptidase (DPP) inhibitors
weight loss
using weight-loss medications
pregnant or lactating

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02180646). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.