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N/A N=248 Randomized Triple-blind Treatment

Postoperative Management for Degenerative Spinal Conditions

Spinal Degenerative Disorder

Enrolled (actual)
248
Serious AEs
0.0%
Results posted
Aug 2019
Primary outcome: Primary: Oswestry Disability Index (ODI) — 43.6; 45.46; 31.31; 31.19 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
CBPT (Behavioral); Education (Other)
Age
Adult, Older Adult · 21+ yrs
Sex
All
Sponsor
Vanderbilt University Medical Center
Primary completion
Nov 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Oswestry Disability Index (ODI)
43.6; 45.46; 31.31; 31.19; 24.06; 24.33
PRIMARY
Brief Pain Inventory (BPI)
6.79; 6.64; 3.15; 3.14; 2.82; 2.69
PRIMARY
12-Item Short Form Health Survey (SF-12)
27.84; 27.8; 33.49; 33.55; 39.31; 38.81
SECONDARY
Physical Activity
432.17; 421.77; 484.29; 487.93; 474.29; 480.42

Summary

The overall objective of this study is to conduct a two-group randomized control trial (RCT) to compare which of two treatments provided by telephone - a cognitive-behavioral based physical therapy (CBPT) program focusing on self-management strategies or an education program about postoperative recovery - are more effective for improving patient-centered outcomes in older adults recovering from lumbar spine surgery for degenerative conditions. Our central hypothesis is that the CBPT intervention focusing on self-management will decrease pain and disability and improve general health, physical activity and physical function in community-dwelling adults undergoing spine surgery, through reductions in fear of movement and increases in pain self-efficacy.

Eligibility Criteria

Inclusion Criteria

  • Radiographic evidence of lumbar spinal stenosis secondary to degenerative changes
  • Surgical treatment of a lumbar degenerative condition (spinal stenosis, spondylosis with or without myelopathy, and degenerative spondylolisthesis) using laminectomy with or without arthrodesis procedures
  • English speaking due to feasibility of employing study personnel to deliver and assess the study intervention
  • Age older than 21 years (younger individuals do not typically have a lumbar degenerative condition).

Exclusion Criteria

  • Patients having microsurgical techniques as the primary procedure, such as an isolated laminotomy or microdiscectomy (individuals having these minimally invasive surgical techniques tend to have a less severe case of lumbar degeneration and a shorter recovery time than individuals having arthrodesis or laminectomy without arthrodesis)
  • Patients having surgery for spinal deformity as the primary indication (patients with spinal deformity as the primary spinal disorder tend to have a different recovery trajectory compared to the inclusion population)
  • Patients having surgery secondary to pseudarthrosis, trauma, infection, or tumor
  • Presence of back and/or lower extremity pain < 3 months indicating no history of chronic pain
  • History of neurological disorder or disease, resulting in moderate to severe movement dysfunction. Including but not limited to Parkinson's disease, Multiple Sclerosis, Epilepsy, Brain tumors, Huntington's disease, Alzheimer's disease, Muscular Dystrophy, Stroke, Autonomic Nervous System disorders, Traumatic Brain Injury, Cerebral Palsy, and Amyotrophic Lateral Sclerosis
  • Presence of schizophrenia or other psychotic disorder, including but not limited to Brief Psychotic disorder and Delusional disorder
  • Patients not able to return to clinic for standard follow-up visits with surgeon due to time and travel limitation
  • Patients having surgery under a workman's compensation claim
  • Unable to provide a stable address and access to a telephone indicating the inability to participate in either the telephone-based CBPT or education program.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02184143). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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