N/A N=60 Randomized Double-blind Treatment

Effectiveness of Two Water-Based Potassium Oxalate Desensitizers

Dentin Sensitivity

Bottom Line

View on ClinicalTrials.gov: NCT02192307 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Nov 2019

Primary outcome: Primary: Change From Baseline Air Challenge — -0.98; -0.97 units on a scale

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Potassium oxalate (Device)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Procter and Gamble
Primary completion: Sep 2014

Outcome Measures

Outcome	Result	p-value
PRIMARY Change From Baseline Air Challenge	-0.98; -0.97	—
SECONDARY Change From Baseline Visual Analog Scale	-38.10; -32.62	—

Summary

This study will compare the safety and effectiveness of two water-based potassium oxalate desensitizers on existing dentinal hypersensitivity.

Eligibility Criteria

Inclusion Criteria

Provide written informed consent to participate in the study
Be at least 18 years of age
Be in good general health, as determined by the Investigator/designee based on review of the health history/update for participation in the study
Agree to refrain from participating in any other oral/dental product studies for the duration of the study
Agree to refrain from receiving any elective dentistry (including dental prophylaxis) for the duration of the study
Agree to refrain from using any oral hygiene products other than the assigned study products for the duration of the study
Agree to comply with study/product usage instructions; and
Have at least one tooth with gingival recession and hypersensitivity evidenced by a score of ≥ 1 on the Cold Air Sensitivity Schiff scale during screening

Exclusion Criteria

Gross oral neglect or urgent dental treatment needs
Severe periodontal disease and/or generalized mobility
Active treatment for periodontitis
Any disease or condition that could be expected to interfere with examination procedures or safe completion of the study
Self-reported pregnancy or nursing

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02192307). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.