Phase 3 N=626 The Efficacy of a Toothpaste to Reduce Sensitivity
Dentin Hypersensitivity
Primary: Hypersensitivity Tactile(Yeaple Probe) — 19.81; 13.94 units on a scale — p=0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=79 Clinical Efficacy of a Toothpaste on Hypersensitivity Reduction
Hypersensitivity
Primary: Tooth Hypersensitity to Touch Stimuli (Tactile) — 10.83; 10.63 Units on a scale — p=0.05
Phase 3 N=118 The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Mean Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Week 8 — -0.9; -0.5 Score on a scale — p=<0.0001
N/A N=120 Study to Evaluate the Effectiveness of Test Dentifrice in the Relief of Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Adjusted Mean Change From Baseline in Schiff Sensitivity Score at Week 12 (Test Dentifrice Versus [vs] Negative Control Dentifrice) — -1.19; -0.44 score on a scale…
N/A N=215 A Clinical Study to Evaluate the Anti-Sensitivity Effect of a Calcium Sodium Phosphosilicate Toothpaste in a Population of Dentin Hypersensitivity Sufferers
Dentin Sensitivity
Primary: Adjusted Mean Change From Baseline in Schiff Sensitivity Score at Day 56 — -2.00; -0.20 score on a scale — p=<0.0001
N/A N=263 A Study to Measure the Efficacy of a Toothpaste on Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Thermo-evaporative (Schiff Air Blast) Stimuli — 2.188; 2.246; 1.268; 1.811 score on a scale — p=<0.001
Phase 3 N=113 Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Day 14 — -1.20; -0.37 Score on a scale — p=<0.0001
N/A N=192 Trial of Nano-hydroxyapatite-Containing Toothpastes for Relief of Dentin Hypersensitivity
Dentin Sensitivity
Primary: Measurement of Cold Air Stimulus — 71.4; 72.2; 71.9; 51.1 units on a scale
N/A N=120 A Clinical Study to Assess the Effects of Various Dentifrice Technologies on Dentinal Hypersensitivity
Dentin Hypersensitivity
Primary: Air Challenge — 1.17; 1.48; 2.26; 1.39 score on a scale
N/A N=79 Instant and Lasting Relief Effects of Strontium Chloride/Potassium Nitrate Dentifrice on Dentin Hypersensitivity
Dentine Hypersensitivity
Primary: Tactile Hypersensitivity Scores Immediately After Topical Dentifrice Use — 19.47; 14.27 gram
Phase 3 N=120 The Efficacy of a Dentifrice in Providing Relief From Immediate and Short Term Relief From Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Change From Baseline in Schiff Sensitivity Score on Day 14 — 2.51; 2.51; 1.16; 1.35 score on a scale — p=0.1774
N/A N=104 Clinical Study to Evaluate the Anti-sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers
Dentin Sensitivity
Primary: Adjusted Mean Change From Baseline in Schiff Sensitivity Score at Day 56 — -2.25; -0.31 score on a scale — p=<0.0001
N/A N=230 The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score on Day 3 — -0.96; -0.77 Score on a scale — p=0.1575
N/A N=204 The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity (DH)
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score on Day 3 — -1.37; -0.45 score on a scale — p=<.0001
N/A N=36 Effects of an Oxalate Containing Product on Dentinal Hypersensitivity With Dental Prophylaxis
Dentin Sensitivity
Primary: Change From Baseline Air Challenge — -0.412; -0.132 Units on a scale
N/A N=22 A Clinical Study to Compare Professional Treatments for Dentinal Hypersensitivity
Dentinal Hypersensitivity
Primary: Change From Baseline Air Challenge — -0.55; -0.95 Units on a scale
Phase 3 N=140 Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH
Dentin Hypersensitivity
Primary: Percent Change in Mean Score of Pain Response From Baseline on Schiff Cold Air Sensitivity Scale Using Air Blast Stimulus — 18; 45; 37; 15 percentage of change in mean…
N/A N=135 Assessment of the Efficacy of an Experimental Occlusion Technology Dentifrice in Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score at Week 8 — -0.94; -0.33 score on a scale — p=<.0001
N/A N=304 Clinical Study to Evaluate the Efficacy of Two Dentifrices for Dentine Hypersensitivity
Dentine Sensitivity
Primary: Mean Change From Baseline in Evaporative Air Sensitivity as Measured by Visual Analogue Score (VAS) at Week 8 — 53.05; 55.89; 31.62; 30.51 score on a scale — p=0.2678
N/A N=113 A Clinical Study to Evaluate the Anti-Sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers
Dentin Sensitivity
Primary: Adjusted Mean Change From Baseline in Schiff Sensitivity Score at Day 56 — -1.40; -0.33 score on a scale — p=<0.0001
Phase 1 N=12 The Effects of Potassium Nitrate in Reducing Dentinal Hypersensitivity
Dentinal Hypersensitivity · Dental Pain
Primary: Adjusted Mean Change From Baseline in Evaporative Sensitivity Pain Response of Hypersensitive Tooth on a Visual Analogue Scale (VAS) Immediately Post Application of 5%…
Phase 2 N=134 Exploratory Study to Evaluate an Occlusion Based Dentifrice in Relief of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Change From Baseline in Evaporative Air Sensitivity Pain Response on Schiff Sensitivity Scale at Week 4 — -0.36; -0.43; -0.40; -0.45 Score on a scale — p=0.4553
Phase 2 N=32 Efficacy of Potassium Nitrate Solution in Reducing Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Between Treatment Comparison of the Adjusted Mean Change From Baseline of Response to Evaporative (Air) Stimuli Immediately Following Treatment on Day 5 Using a Visual…
N/A N=75 Impact of Long Term Management of Dentine Hypersensitivity (DH) With a Daily Use Anti-sensitivity Toothpaste on the Quality of Life Related to Oral Health
Dentin Sensitivity
Primary: Change From Baseline in Mean Total Score (34 Item Total From Section 2) of Dentine Hyersensitivity Experience Questionnaire (DHEQ) at Week 4 — 142.41; 135.24; -6.28…
N/A N=233 The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity(DH)
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score on Day 3 — -1.40; -0.38 Score on a scale — p=<0.0001
N/A N=30 A Pilot Study to Assess Nominal Versus Controlled Stimuli on Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline for Visual Analog Scale - Cold Water — -22.93 Units on a scale
N/A N=39 Caries Prevention Products & Dentinal Hypersensitivity
Hypersensitivity
Primary: Dentinal Hypersensitivity — 1; 1; 0; 3 units on a scale — p=0.72
N/A N=30 A Clinical Study of Two Dentinal Hypersensitivity Treatments Used With Normal Oral Hygiene
Dentin Sensitivity
Primary: Change From Baseline Air Challenge — -1.643; -1.500 Units on a scale
N/A N=60 Effectiveness of Two Water-Based Potassium Oxalate Desensitizers
Dentin Sensitivity
Primary: Change From Baseline Air Challenge — -0.98; -0.97 units on a scale
N/A N=655 A Real-World Evidence Study to Evaluate Oral Health Related Quality of Life Using an Anti-Sensitivity Toothpaste
Dentin Sensitivity
Primary: Mean Score of DHEQ Section 1 - Impact on Everyday Life (Question [Q]1-3) at Baseline (Day 0) — 5.90; 6.17; 5.20 score on a scale