N/A
Completed N=246
Smartphone-Delivered Attentional Bias Modification Training in Helping Patients Quit Smoking
Current Every Day Smoker
Source: ClinicalTrials.gov NCT02224391 ↗
Enrolled (actual)
246
Serious AEs
2.4%
Results posted
Sep 2022
Primary outcomePrimary: Modified Dot-probe Task — 5.49; 7.49; 2.42; 9.85 milliseconds
Summary
This randomized clinical trial studies how well a smartphone-delivered attentional bias modification training works in helping patients quit smoking. Smartphone-delivered attentional bias modification training may help patients quit smoking by reducing the attentional bias (the tendency of one's perception to be affected by their recurring thoughts) towards smoking cues that developed over time as a result of conditioning processes through which smoking cues become important.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Modified Dot-probe Task |
5.49; 7.49; 2.42; 9.85; 4.94; 9.48 | — |
| PRIMARY Smoking Stroop Task |
-6.57; 4.94; -2.38; 3.73; -4.59; 10.97 | — |
| SECONDARY Cigarette Per Day (CPD) |
18.1; 18.45; 14.94; 14.78; 8.29; 7.52 | — |
| SECONDARY Expired Carbon Monoxide (CO) |
22.41; 22.27; 22.28; 22.95; 12.54; 12.99 | — |
| SECONDARY Urinary Cotinine |
7.11; 7.12; 6.91; 6.99; 6.16; 6.61 | — |
| SECONDARY Fagerström Test for Nicotine Dependence (FTND) |
4.84; 4.96; 4.34; 4.05; 2.93; 2.65 | — |
| SECONDARY Wisconsin Smoking Withdrawal Scale (WSWS) - Craving |
9.9; 9.76; 8.36; 8.52; 6.92; 6.73 | — |
Eligibility Criteria
Inclusion Criteria
- Smoke an average of 5 or more cigarettes or little cigars per day (CPD) prior to telephone screen
- Produce an expired carbon monoxide (CO) level greater than or equal to 6 parts per million (ppm) or a NicAlert reading of > 2
- Have a working telephone
- Interested in quitting smoking in the next 30 days
- Fluency in spoken and written English
- Must sign the picture consent form
Exclusion Criteria
- Taking psychotropic, anticonvulsive, or narcotic medication
- Meet criteria for a current major depressive episode or suicidality
- Have a history of neurological illness or closed head injury
- Report uncorrected vision problems
- Involved in current smoking cessation activity
- Testing positive on a urine drug screen for drugs of abuse/potential abuse
- Women who are pregnant or breastfeeding
- Considered by the investigator to be an unsuitable or unstable candidate (e.g., due to cognitive impairment)
- Shares the same address as a currently enrolled participant
- Unwilling to alter or remove hairstyle, hair extensions, or wig during the clinic visits to allow for correct electroencephalography (EEG) sensor placement
- Reports diagnosis of seizure disorder
- Unwilling to use nicotine replacement therapy (NRT) patches
Data sourced from ClinicalTrials.gov (NCT02224391). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.