N/A N=3 Randomized Single-blind Treatment

Transcranial Direct Stimulation (tDCS) and Behavioral Intervention in Aphasia

Aphasia

Bottom Line

View on ClinicalTrials.gov: NCT02226796 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Feb 2021

Primary outcome: Primary: Naming Reaction Time — 1829.11; 3345.97 milliseconds

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Transcranial direct current stimulation (Device)
Age: Adult, Older Adult · 20+ yrs
Sex: All
Sponsor: University of Minnesota
Primary completion: Dec 2018

Outcome Measures

Outcome	Result	p-value
PRIMARY Naming Reaction Time	1829.11; 3345.97	—
PRIMARY Naming Accuracy	5.95; 6.044	—
SECONDARY Boston Naming Test	—	—
SECONDARY Western Aphasia Battery Total Score	—	—
SECONDARY Working Memory Total Score	—	—

Summary

We hypothesize patients who have difficulty with word recall (naming pictures) due to a stroke will experience greater benefit in word recall after receiving a combination of transcranial direct current stimulation (tDCS) and traditional behavioral treatment. This study will investigate the effects of the timing of tDCS in relationship to the behavioral treatment to determine the most optimal protocol. Transcranial direct current stimulation involves placing two electrodes on your scalp and sending a very small electrical current to excite the brain cells of the target site.

Eligibility Criteria

Inclusion Criteria

completion of high school or GED, normal or corrected-to-normal vision, adequate hearing acuity for 1:1 conversational exchanges, use of English as primary language, a vascular lesion in the dominant left hemisphere verified by an MRI scan within six months of the start of the study

Exclusion Criteria

no previous history of neurological- or psychiatric-based illnesses or disease, language or learning disabilities, or alcohol/substance abuse; no history of seizures; no metal implants in the head (except dental fillings); no lesion in the left DLPFC confirmed by MRI; no current pregnancy.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02226796). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.