N/A
Completed N=8
Value of Patch Testing in Direct Diet Therapy for Eosinophilic Esophagitis
Source: ClinicalTrials.gov NCT02227836 ↗Enrolled (actual)
8
Serious AEs
0.0%
Results posted
Apr 2019
Primary outcomePrimary: Sensitivity of Patch Testing — 1 Participants
Summary
This study is being done to see if allergy patch testing (APT) can help predict effective dietary therapy in patients with eosinophilic esophagitis.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Sensitivity of Patch Testing |
1 | — |
Eligibility Criteria
Inclusion criteria
- Adults ages 18-90
- Patients with EoE, defined as dysphagia with histologic finding of greater than or equal to 15 eosinophils per high powered field (eos per HPF) on index esophageal biopsy
- Persistent symptoms and/or greater than or equal to 10 eos per HPF on esophageal biopsy after at least 8 weeks of twice daily PPI therapy
Exclusion criteria
- Patients with conditions known to be associated with esophageal eosinophilia, including Crohn's disease, Churg-Strauss, achalasia, and hypereosinophilic syndrome
- Topical swallowed steroids within 8 weeks of study enrollment
- Dermatologic conditions precluding application of Finn chambers to the skin for APT
- Inability to read due to: Blindness, cognitive dysfunction, or English language illiteracy
Data sourced from ClinicalTrials.gov (NCT02227836). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.