N/A
N=505
Impact of Family History and Decision Support on High-risk Cancer Screening
Colorectal Cancer
Bottom Line
View on ClinicalTrials.gov: NCT02247336 ↗Enrolled (actual)
505
Serious AEs
0.0%
Results posted
Aug 2021
Primary outcome: Primary: Number of Patients With Provider Referral for Risk-appropriate Colorectal Cancer Screening — 219; 232 Participants — p=0.16
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Family health history platform (MeTree) (Behavioral)
- Age
- Adult · 40+ yrs
- Sex
- All
- Sponsor
- VA Office of Research and Development
- Primary completion
- Jul 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Patients With Provider Referral for Risk-appropriate Colorectal Cancer Screening |
219; 232 | 0.16 |
| SECONDARY Number of Participants Who Received Recommended Colorectal Cancer Screening |
55; 68 | 0.23 |
| SECONDARY Number of Patients Who Received Referral for Genetic Consultation |
1; 1 | — |
Summary
Family health history can help identify patients at higher than average risk for disease. There is no standardized system for collecting and updating family health history, using this information to determine a patient's disease risk level, and providing screening recommendations to patients and providers. Patients will enter their family health history into MeTree, a family history software program. The program will produce screening recommendations tailored to the patient's family health history. The investigators will examine whether this process increases physician referrals for, and patient uptake of, guideline-recommended screening for colorectal cancer.
Eligibility Criteria
Inclusion Criteria
Primary care provider inclusion criteria:
- primary care physician,
- physician assistant, or nurse practitioner;
- at least one half-day of primary care clinic per week.
Patient inclusion criteria:
- assigned to an enrolled PCP;
- English as preferred language;
- no plans to relocate or leave the VA system in the next 12 months;
- at least one primary care appointment in the 18 months prior to enrollment;
- upcoming PCP appointment with assigned PCP;
- aged 40-64 years; no previous history of colorectal cancer or adenomatous polyps or inflammatory bowel disease;
- no endoscopy within previous 3 years; some knowledge of family health history
Exclusion Criteria
n/a (contained within inclusion criteria)
Data sourced from ClinicalTrials.gov (NCT02247336). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.