N/A
N=160
Telemedicine Intervention to Improve Cognitive Function
Parkinson's Disease
Bottom Line
View on ClinicalTrials.gov: NCT02248649 ↗Enrolled (actual)
160
Serious AEs
11.3%
Results posted
Jul 2019
Primary outcome: Primary: Change From Baseline on Cognitive Section of Alzheimer Disease Assessment Scale (ADAS-Cog) at Month 6 — -0.24; 0.95 score on a scale — p=0.2
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Structured physical activity (Behavioral); Health education (Behavioral)
- Age
- Adult, Older Adult · 40+ yrs
- Sex
- All
- Sponsor
- VA Office of Research and Development
- Primary completion
- May 2018
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change From Baseline on Cognitive Section of Alzheimer Disease Assessment Scale (ADAS-Cog) at Month 6 |
-0.24; 0.95 | 0.2 |
| SECONDARY Change From Baseline on Cognitive Section of Alzheimer Disease Assessment Scale (ADAS-Cog) at Month 12 |
0.12; 2.60 | 0.04 sig |
| SECONDARY Change From Baseline on Cognitive Section of Alzheimer Disease Assessment Scale (ADAS-Cog) at Month 18 |
0.40; 3.60 | 0.02 sig |
Summary
This project is investigating whether a home-based exercise program will reduce cognitive decline in patients with Parkinson's disease.
Eligibility Criteria
Inclusion Criteria
- Physician diagnosis of idiopathic, typical Parkinson's disease (PD)
- At least 2 of 3 cardinal signs of PD
- Response to dopaminergic medication
- Mild cognitive impairment
Exclusion Criteria
- Angina pectoris
- History of myocardial infarction within 6 months
- History of ventricular dysrhythmia requiring current therapy
Data sourced from ClinicalTrials.gov (NCT02248649). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.